| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.600 | None | 0.921 | 203 | 3 | 1992 | 2020 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.300 | None | 0.919 | 86 | 1 | 1999 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.901 | 71 | 1 | 2000 | 2020 | ||||||||
|
serpin family E member 1 | 0.359 | 0.885 | 4.4E-02 |
|
disease | 0.300 | None | 0.928 | 69 | 4 | 1995 | 2018 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.600 | None | 0.955 | 67 | 7 | 1991 | 2020 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.600 | None | 0.915 | 59 | 3 | 1998 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 1.000 | 58 | 2 | 2001 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.600 | None | 0.961 | 51 | 2 | 2000 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.400 | None | 0.959 | 49 | 7 | 1986 | 2020 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.600 | None | 0.980 | 49 | 2 | 1995 | 2019 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.400 | None | 0.958 | 48 | 1 | 1991 | 2019 | ||||||||
|
plasminogen activator, tissue type | 0.445 | 0.885 | 5.7E-05 |
|
disease | 0.400 | None | 0.978 | 45 | 0 | 1986 | 2019 | ||||||||
|
lipoprotein(a) | 0.444 | 0.769 | 6.6E-89 |
|
disease | 0.200 | None | 0.951 | 41 | 2 | 1988 | 2020 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.100 | None | 0.947 | 38 | 6 | 1996 | 2019 | ||||||||
|
coagulation factor II, thrombin | 0.415 | 0.885 | 1.1E-03 |
|
disease | 0.400 | None | 0.892 | 37 | 4 | 1997 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.600 | None | 1.000 | 37 | 2 | 2001 | 2020 | ||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
disease | 0.300 | None | 0.882 | 34 | 2 | 1994 | 2019 | ||||||||
|
apolipoprotein B | 0.453 | 0.808 | 1.9E-16 |
|
disease | 0.200 | None | 0.968 | 31 | 5 | 1986 | 2020 | ||||||||
|
troponin I3, cardiac type | 0.520 | 0.769 | 9.6E-02 |
|
disease | 0.400 | None | 1.000 | 30 | 0 | 2001 | 2019 | ||||||||
|
lymphotoxin alpha | 0.434 | 0.885 | 0.20 |
|
disease | 0.500 | None | 0.926 | 27 | 3 | 2001 | 2018 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.600 | None | 1.000 | 27 | 5 | 1996 | 2019 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.200 | None | 0.889 | 27 | 3 | 2004 | 2019 | ||||||||
|
cholesteryl ester transfer protein | 0.512 | 0.731 | 1.2E-23 |
|
disease | 0.100 | None | 0.923 | 26 | 7 | 1991 | 2018 | ||||||||
|
coagulation factor V | 0.441 | 0.846 | 5.9E-15 |
|
disease | 0.400 | None | 0.962 | 26 | 2 | 1995 | 2019 | ||||||||
|
apolipoprotein A1 | 0.429 | 0.885 | 5.5E-04 |
|
disease | 0.100 | None | 0.846 | 26 | 1 | 1986 | 2019 |