×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Genotype-Phenotype Correlation of SCN5A Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome: A Japanese Multicenter Registry.
28341781 2017
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Facilitatory and inhibitory effects of SCN5A mutations on atrial fibrillation in Brugada syndrome.
21273195 2011
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
A comprehensive electrocardiographic, molecular, and echocardiographic study of Brugada syndrome: validation of the 2013 diagnostic criteria.
24721456 2014
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Substitution of a conserved alanine in the domain IIIS4-S5 linker of the cardiac sodium channel causes long QT syndrome.
16039271 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Identification of six novel SCN5A mutations in Japanese patients with Brugada syndrome.
21321465 2011
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation.
9521325 1998
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Targeted Next-Generation Sequencing of 51 Genes Involved in Primary Electrical Disease.
28341588 2017
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations.
16325048 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Cardiac Na(+) channel dysfunction in Brugada syndrome is aggravated by beta(1)-subunit.
10618304 2000
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Genetic Variation of SCN5A in Korean Patients with Sick Sinus Syndrome.
26798387 2016
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Sodium channelopathy underlying familial sick sinus syndrome with early onset and predominantly male characteristics.
24762805 2014
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of Brugada or long QT syndrome.
23840796 2013
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Comparison of long-term follow-up of electrocardiographic features in Brugada syndrome between the SCN5A-positive probands and the SCN5A-negative probands.
17697823 2007
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
A mutant cardiac sodium channel with multiple biophysical defects associated with overlapping clinical features of Brugada syndrome and cardiac conduction disease.
11827685 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
[Novel SCN5A gene mutations associated with Brugada syndrome: V95I, A1649V and delF1617].
17081365 2006
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
The Brugada ECG and schizophrenia.
24951569 2014
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
We screened patients with SUNDS for mutations in SCN5A , the gene known to cause Brugada syndrome , as well as genes encoding ion channels associated with the long-QT syndrome.
11823453 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A).
14523039 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
GWASCAT
Common variants at SCN5A -SCN10A and HEY2 are associated with Brugada syndrome , a rare disease with high risk of sudden cardiac death.
23872634 2013
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Absence of pathognomonic or inflammatory patterns in cardiac biopsies from patients with Brugada syndrome.
19808440 2009
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.
12693506 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Here, we report the functional consequences of a novel missense SCN5A mutation, G1319V, identified in a BrS patient.
17854786 2007
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Clinical application of exome sequencing in undiagnosed genetic conditions.
22581936 2012
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Clinical exome sequencing for genetic identification of rare Mendelian disorders.
25326637 2014
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
In families with Brugada syndrome , the data suggest that ajmaline testing is valuable in the diagnosis of SCN5A carriers.
15520322 2004