Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 25
Gene Symbol: ABL1
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase 0.432 0.923 1.00
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.100 None 1.000 34 1 1991 2019
Entrez Id: 947
Gene Symbol: CD34
CD34
CD34 molecule 0.368 0.808 5.0E-06
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.100 None 1.000 10 0 1999 2019
Entrez Id: 54790
Gene Symbol: TET2
TET2
tet methylcytosine dioxygenase 2 0.458 0.808 4.3E-54
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.360 None 1.000 8 0 2009 2016
Entrez Id: 5542
Gene Symbol: PRB1
PRB1
proline rich protein BstNI subfamily 1 (gene/pseudogene) 0.621 0.692 8.4E-11
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.070 None 1.000 7 0 2015 2019
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
interferon alpha 2 0.442 0.885
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.360 None 1.000 7 0 1989 2014
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
interferon alpha 13 0.374 0.923
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.060 None 1.000 6 0 1998 2019
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
interferon alpha 1 0.371 0.923
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.060 None 1.000 6 0 1998 2019
Entrez Id: 2056
Gene Symbol: EPO
EPO
erythropoietin 0.381 0.885 1.1E-02
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.060 None 1.000 6 0 2003 2008
Entrez Id: 367
Gene Symbol: AR
AR
androgen receptor 0.351 0.846 0.99
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.050 None 1.000 5 0 1995 2012
Entrez Id: 6427
Gene Symbol: SRSF2
SRSF2
serine and arginine rich splicing factor 2 0.561 0.731 0.48
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.050 None 1.000 5 0 2016 2017
Entrez Id: 102606463
Gene Symbol: LINC01152
LINC01152
long intergenic non-protein coding RNA 1152 0.729 0.231
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.050 None 1.000 5 0 2006 2007
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.050 None 1.000 5 0 2002 2014
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3
SH2B adaptor protein 3 0.527 0.692 1.0E-04
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.520 None 1.000 4 4 2011 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.030 None 1.000 3 0 2009 2013
Entrez Id: 4778
Gene Symbol: NFE2
NFE2
nuclear factor, erythroid 2 0.628 0.577 0.67
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.030 None 1.000 3 0 2002 2014
Entrez Id: 79139
Gene Symbol: DERL1
DERL1
derlin 1 0.576 0.654 2.1E-04
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.030 None 1.000 3 0 2005 2011
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
suppressor of cytokine signaling 3 0.434 0.808 0.75
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.030 None 1.000 3 0 2008 2016
Entrez Id: 2152
Gene Symbol: F3
F3
coagulation factor III, tissue factor 0.415 0.846 1.9E-02
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.030 None 1.000 3 0 2009 2016
Entrez Id: 4602
Gene Symbol: MYB
MYB
MYB proto-oncogene, transcription factor 0.490 0.692 0.82
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.220 None 1.000 3 0 2010 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.030 None 1.000 3 0 2004 2014
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
lipocalin 2 0.405 0.885 1.1E-09
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.020 None 1.000 2 0 2011 2016
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
Fli-1 proto-oncogene, ETS transcription factor 0.468 0.692 0.99
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.020 None 1.000 2 0 2006 2019
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
glucose-6-phosphate dehydrogenase 0.424 0.846 0.97
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.020 None 1.000 2 0 1982 1983
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene, receptor tyrosine kinase 0.366 0.808 0.98
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.020 None 1.000 2 0 2007 2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.320 None 1.000 2 0 2004 2005