Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0702169
Disease: Acrania
Acrania 		0.300 Biomarker CTD_human

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.500 Biomarker CTD_human Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants. 15585374

2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.500 Biomarker CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0458247
Disease: Allodynia
Allodynia 		0.300 Biomarker CTD_human Chemical interactions between fibrosarcoma cancer cells and sensory neurons contribute to cancer pain. 17881535

2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Elevated levels of MCP-1, MIP-alpha and MIP-1 beta in the bronchoalveolar lavage (BAL) fluid of patients with mustard gas-induced pulmonary fibrosis. 17720292

2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Role of human pulmonary fibroblast-derived MCP-1 in cell activation and migration in experimental silicosis. 26163174

2015
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice. 16324872

2006
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0750987
Disease: Arterial Diseases, Common Carotid
Arterial Diseases, Common Carotid 		0.300 Biomarker CTD_human Risk of carotid atherosclerosis associated with genetic polymorphisms of apolipoprotein E and inflammatory genes among arsenic exposed residents in Taiwan. 18022660

2008
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004096
Disease: Asthma
Asthma 		0.600 Biomarker CTD_human In asthma patients, the consistently elevated serum levels of MCP-1 suggest its role in the pathogenesis of bronchial asthma - not only in the chronic inflammatory processes, but also in acute asthma attack exacerbation. 19373627

2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1563937
Disease: Atherogenesis
Atherogenesis 		0.300 Biomarker CTD_human Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. 20720404

2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1563937
Disease: Atherogenesis
Atherogenesis 		0.300 Biomarker CTD_human Atheroprotective Mechanisms Activated by Fluid Shear Stress in Endothelial Cells. 12677255

2002
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1563937
Disease: Atherogenesis
Atherogenesis 		0.300 Biomarker CTD_human Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects. 12928151

2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker CTD_human Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects. 12928151

2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker CTD_human Atheroprotective Mechanisms Activated by Fluid Shear Stress in Endothelial Cells. 12677255

2002
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker CTD_human Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. 20720404

2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
Autoimmune Chronic Hepatitis 		0.300 Biomarker CTD_human Involvement of T helper 17 cells in D-penicillamine-induced autoimmune disease in Brown Norway rats. 21227906

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0917713
Disease: Becker Muscular Dystrophy
Becker Muscular Dystrophy 		0.300 Biomarker CTD_human Inhibiting TGF-β activity improves respiratory function in mdx mice. 21641384

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.510 Biomarker CTD_human Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. 17394460

2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.510 Biomarker CTD_human Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. 15829914

2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1704377
Disease: Bright Disease
Bright Disease 		0.300 Biomarker CTD_human Gene expression of CC chemokines in experimental acute tubulointerstitial nephritis. 10385480

1999
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0085129
Disease: Bronchial Hyperreactivity
Bronchial Hyperreactivity 		0.500 Biomarker CTD_human Leukotrienes, IL-13, and chemokines cooperate to induce BHR and mucus in allergic mouse lungs. 12388339

2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0006663
Disease: Calcinosis
Calcinosis 		0.300 Biomarker CTD_human Raloxifene attenuates Gas6 and apoptosis in experimental aortic valve disease in renal failure. 21335463

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0006663
Disease: Calcinosis
Calcinosis 		0.300 Biomarker CTD_human Eicosapentaenoic acid reduces warfarin-induced arterial calcification in rats. 21193197

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0876994
Disease: Cardiotoxicity
Cardiotoxicity 		0.300 Biomarker CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987

2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.400 Biomarker CTD_human Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production. 16332659

2005