Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 966
Gene Symbol: CD59
CD59
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.240 Biomarker RGD Loss of CD59 in the AMI lesions was observed in association with deposits of MAC from day one onward. 7515561

1994

Entrez Id: 731
Gene Symbol: C8A
C8A
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. 7515561

1994

Entrez Id: 732
Gene Symbol: C8B
C8B
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. 7515561

1994

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker RGD Regulation of collagen degradation in the rat myocardium after infarction. 8531210

1995

Entrez Id: 4312
Gene Symbol: MMP1
MMP1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Regulation of collagen degradation in the rat myocardium after infarction. 8531210

1995

Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Myocardial infarction and the myocyte IGF1 autocrine system. 8682060

1995

Entrez Id: 2535
Gene Symbol: FZD2
FZD2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD A homologue of Drosophila tissue polarity gene frizzled is expressed in migrating myofibroblasts in the infarcted rat heart. 9142123

1997

Entrez Id: 6382
Gene Symbol: SDC1
SDC1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD To examine experimentally the sequential changes in syndecan-1 and fibroglycan messenger RNA (mRNA) expression after acute myocardial infarction. 9237025

1997

Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.520 Biomarker RGD Pattern of superoxide dismutase enzymatic activity and RNA changes in rat heart ventricles after myocardial infarction. 9250167

1997

Entrez Id: 5331
Gene Symbol: PLCB3
PLCB3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Expression of Gq alpha and PLC-beta in scar and border tissue in heart failure due to myocardial infarction. 9521338

1998

Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Expression of Gq alpha and PLC-beta in scar and border tissue in heart failure due to myocardial infarction. 9521338

1998

Entrez Id: 4192
Gene Symbol: MDK
MDK
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Myocardial infarction induces expression of midkine, a heparin-binding growth factor with reparative activity. 9568069

1998

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Alterations in sarcoplasmic reticulum and angiotensin II type 1 receptor gene expression after myocardial infarction in rats. 9652322

1998

Entrez Id: 4191
Gene Symbol: MDH2
MDH2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Effect of alpha-tocopherol on mitochondrial electron transport in experimental myocardial infarction in rats. 9753871

1998

Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Elevation of expression of Smads 2, 3, and 4, decorin and TGF-beta in the chronic phase of myocardial infarct scar healing. 10198196

1999

Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Elevation of expression of Smads 2, 3, and 4, decorin and TGF-beta in the chronic phase of myocardial infarct scar healing. 10198196

1999

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo. 10573185

1999

Entrez Id: 1907
Gene Symbol: EDN2
EDN2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo. 10573185

1999

Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker RGD Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat. 10773235

2000

Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Some MMPs were significantly elevated during the first week post-MI (MMP-13, -2, and -9) and another was not until 16 weeks post-MI (MMP-14). 10773235

2000

Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Identification of regulated genes in rat heart after myocardial infarction by means of differential mRNA display. 10807530

2000

Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.260 Therapeutic RGD Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro. 11087260

2000

Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Therapeutic RGD Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro. 11087260

2000

Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker RGD ET(A)-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat. 11179039

2001

Entrez Id: 4312
Gene Symbol: MMP1
MMP1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD ET(A)-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat. 11179039

2001