Source: BEFREE
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1992 | 2014 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.917 | 11 | 1 | 1993 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2001 | 2014 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2003 | 2003 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.040 | None | 1.000 | 3 | 0 | 1989 | 2002 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2009 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2010 | 2018 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2010 | 2011 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2013 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2002 | 2016 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2011 | 2011 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1994 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 2008 | 2019 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1993 | 2004 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1990 | 2018 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2005 | 2006 | ||||||||
|
C-X-C motif chemokine receptor 4 | 0.362 | 0.923 | 1.8E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 |