| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.600 | strong | 0.974 | 114 | 36 | 1988 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.800 | strong | 0.972 | 359 | 34 | 1990 | 2020 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.800 | strong | 0.973 | 485 | 32 | 1993 | 2020 | ||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
disease | 0.500 | strong | 0.947 | 132 | 20 | 2002 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.947 | 665 | 19 | 1989 | 2020 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.800 | strong | 0.971 | 277 | 18 | 1993 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.600 | None | 0.963 | 1007 | 13 | 1990 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.985 | 266 | 13 | 2002 | 2020 | ||||||||
|
prostate cancer associated transcript 1 | 0.575 | 0.615 |
|
disease | 0.140 | None | 1.000 | 23 | 13 | 2007 | 2019 | |||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.991 | 568 | 12 | 1992 | 2020 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.400 | None | 0.932 | 118 | 12 | 1996 | 2019 | ||||||||
|
SMAD family member 7 | 0.470 | 0.769 | 0.55 |
|
disease | 0.500 | None | 0.984 | 63 | 12 | 2001 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.979 | 243 | 11 | 1994 | 2020 | ||||||||
|
cancer susceptibility 8 | 0.670 | 0.462 |
|
disease | 0.140 | None | 1.000 | 23 | 11 | 2007 | 2019 | |||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.976 | 622 | 10 | 2002 | 2020 | ||||||||
|
8-oxoguanine DNA glycosylase | 0.453 | 0.808 | 3.9E-12 |
|
disease | 0.100 | None | 0.690 | 29 | 10 | 2000 | 2019 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.100 | None | 0.844 | 64 | 9 | 2001 | 2019 | ||||||||
|
axin 2 | 0.507 | 0.692 | 0.57 |
|
disease | 0.500 | None | 0.905 | 21 | 9 | 2001 | 2019 | ||||||||
|
POU class 5 homeobox 1B | 0.670 | 0.346 | 2.9E-04 |
|
disease | 0.100 | None | 1.000 | 19 | 9 | 2007 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.700 | None | 0.983 | 469 | 8 | 1997 | 2020 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 0.959 | 222 | 8 | 1995 | 2020 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.500 | None | 0.938 | 48 | 8 | 2000 | 2019 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.400 | None | 1.000 | 38 | 8 | 2006 | 2019 | ||||||||
|
fibroblast growth factor receptor 3 | 0.391 | 0.846 | 1.6E-05 |
|
disease | 0.660 | None | 1.000 | 6 | 8 | 2000 | 2018 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.600 | None | 0.960 | 75 | 7 | 1990 | 2020 |