Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0587248
Disease: Costello syndrome (disorder)
Costello syndrome (disorder)
0.600 Biomarker CLINGEN Remarkably, our cohort of individuals with KRAS mutations showed a high clinical variability, ranging from Noonan syndrome to CFC, and also included two patients who met the clinical criteria of Costello syndrome. 17056636

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0587248
Disease: Costello syndrome (disorder)
Costello syndrome (disorder)
0.600 Biomarker CLINGEN We report on a novel KRAS gene mutation in a patient presenting the clinical features typical of Costello syndrome and the additional findings seen in Noonan syndrome. 17468812

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0587248
Disease: Costello syndrome (disorder)
Costello syndrome (disorder)
0.600 Biomarker CLINGEN Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype. 16773572

2006