Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1407
Gene Symbol: CRY1
CRY1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.320 Biomarker PSYGENET We examined 209 single-nucleotide polymorphisms (SNPs) covering 19 circadian genes (ADCYAP1, ARNTL, ARNTL2, BHLHB2, BHLHB3, CLOCK, CRY1, CRY2, CSNK1E, DBP, NPAS2, NR1D1, PER1, PER2, PER3, RORA, TIMELESS, VIP, and VIPR2) in a sample of 534 MD patients (335 with unipolar major mood depression (MDD) and 199 with bipolar disorder (BD)) and 440 community-based screened controls. 20072116

2010

Entrez Id: 1407
Gene Symbol: CRY1
CRY1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.320 Biomarker PSYGENET The findings that have gained support indicate that genetic variants of RORA (rs2028122) and CRY1 (rs2287161) associate with depressive disorder, those of RORB (rs7022435, rs3750420, rs1157358, rs3903529) and NR1D1 (rs2314339) with bipolar disorder, and those of NPAS2 (rs11541353) and CRY2 (rs10838524) with seasonal affective disorder or winter depression. 22538398

2012

Entrez Id: 1407
Gene Symbol: CRY1
CRY1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.320 Biomarker PSYGENET Linkage disequilibrium analyses using single SNPs and haplotypes showed no association to bipolar disease.Additional, more powerful, studies involving Cry1 and other circadian clock genes need to be tested before an association of circadian abnormalities with bipolar disorder can be excluded. 15722957

2005