Source: CURATED
Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
protein tyrosine phosphatase receptor type T | 0.636 | 0.538 | 1.00 |
|
disease | 0.300 | None | 0 | 1 | |||||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.989 | 3 | 0 | 1986 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.500 | None | 1.000 | 2 | 0 | 1987 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.963 | 3 | 0 | 1988 | 2020 | ||||||||
|
gastrin | 0.485 | 0.808 | 2.7E-03 |
|
disease | 0.400 | None | 0.972 | 1 | 0 | 1988 | 2020 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.340 | None | 1.000 | 2 | 0 | 1989 | 2015 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.400 | None | 0.975 | 2 | 0 | 1991 | 2020 | ||||||||
|
transforming growth factor alpha | 0.432 | 0.885 | 0.72 |
|
disease | 0.350 | None | 1.000 | 1 | 0 | 1991 | 2014 | ||||||||
|
thymidylate synthetase | 0.425 | 0.846 | 0.72 |
|
disease | 0.400 | None | 0.938 | 4 | 0 | 1992 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.400 | None | 0.950 | 2 | 0 | 1992 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.912 | 2 | 0 | 1992 | 2019 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.700 | None | 0.983 | 2 | 2 | 1992 | 2019 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.700 | None | 0.950 | 0 | 0 | 1992 | 2019 | ||||||||
|
CD44 molecule (Indian blood group) | 0.363 | 0.962 | 2.4E-07 |
|
disease | 0.400 | None | 0.982 | 1 | 0 | 1993 | 2019 | ||||||||
|
heat shock protein family B (small) member 1 | 0.436 | 0.808 | 2.8E-07 |
|
disease | 0.340 | None | 1.000 | 1 | 0 | 1993 | 2017 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 1994 | 2019 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 1995 | 2019 | ||||||||
|
plasminogen activator, urokinase | 0.425 | 0.923 | 2.3E-06 |
|
disease | 0.380 | None | 1.000 | 1 | 0 | 1995 | 2017 | ||||||||
|
matrix metallopeptidase 7 | 0.446 | 0.885 | 1.0E-09 |
|
disease | 0.400 | None | 0.950 | 1 | 0 | 1995 | 2019 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.800 | None | 0.933 | 6 | 1 | 1996 | 2020 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.700 | None | 0.957 | 2 | 0 | 1996 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.941 | 1 | 0 | 1996 | 2019 | ||||||||
|
serpin family B member 2 | 0.502 | 0.808 | 6.4E-12 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 1996 | 2018 | ||||||||
|
serpin family E member 1 | 0.359 | 0.885 | 4.4E-02 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 1996 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.400 | None | 0.947 | 1 | 0 | 1996 | 2017 |