Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3081
Gene Symbol: HGD
HGD 		homogentisate 1,2-dioxygenase 0.631 0.577 3.0E-08
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 0 0
Entrez Id: 6687
Gene Symbol: SPG7
SPG7 		SPG7 matrix AAA peptidase subunit, paraplegin 0.436 0.885 2.0E-36
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 0 1
Entrez Id: 4161
Gene Symbol: MC5R
MC5R 		melanocortin 5 receptor 0.743 0.423 6.5E-05
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 406948
Gene Symbol: MIR15A
MIR15A 		microRNA 15a 0.482 0.808
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2017 2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		endothelin 1 0.380 0.846 0.46
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 5444
Gene Symbol: PON1
PON1 		paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A 		ATPase copper transporting alpha 0.494 0.769 1.00
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 972
Gene Symbol: CD74
CD74 		CD74 molecule 0.512 0.808 0.25
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 4159
Gene Symbol: MC3R
MC3R 		melanocortin 3 receptor 0.695 0.462 1.0E-07
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 728638
Gene Symbol: KRT8P3
KRT8P3 		keratin 8 pseudogene 3 0.644 0.538
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 3856
Gene Symbol: KRT8
KRT8 		keratin 8 0.517 0.654 2.4E-08
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.020 None 0.500 2 0 2013 2015
Entrez Id: 1298
Gene Symbol: COL9A2
COL9A2 		collagen type IX alpha 2 chain 0.572 0.769 1.0E-08
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 0.750 4 0 2003 2015
Entrez Id: 5903
Gene Symbol: RANBP2
RANBP2 		RAN binding protein 2 0.578 0.615 1.00
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 0.750 4 0 2005 2015
Entrez Id: 7222
Gene Symbol: TRPC3
TRPC3 		transient receptor potential cation channel subfamily C member 3 0.570 0.731 1.1E-07
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 0.750 4 0 2002 2018
Entrez Id: 1638
Gene Symbol: DCT
DCT 		dopachrome tautomerase 0.619 0.654 7.4E-14
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 0.750 4 0 2005 2015
Entrez Id: 7218
Gene Symbol: TRP-AGG2-6
TRP-AGG2-6 		tRNA-Pro (anticodon AGG) 2-6 0.666 0.462
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 0.750 4 0 2005 2015
Entrez Id: 7219
Gene Symbol: TRP-TGG3-1
TRP-TGG3-1 		tRNA-Pro (anticodon TGG) 3-1 0.780 0.269
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 0.750 4 0 2002 2018
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		matrix metallopeptidase 1 0.385 0.885 7.7E-18
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 0.750 4 1 2013 2019
Entrez Id: 1299
Gene Symbol: COL9A3
COL9A3 		collagen type IX alpha 3 chain 0.569 0.769 3.3E-12
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.060 None 0.833 6 0 2002 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 0.875 24 2 1998 2020
Entrez Id: 176
Gene Symbol: ACAN
ACAN 		aggrecan 0.528 0.846 1.00
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 0.962 26 0 2002 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		interleukin 1 beta 0.276 0.962 0.13
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 1.000 31 0 2004 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		tumor necrosis factor 0.231 0.962 0.80
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 1.000 24 0 2013 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		interleukin 6 0.248 0.962 0.32
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 1.000 10 3 2011 2019
Entrez Id: 655
Gene Symbol: BMP7
BMP7 		bone morphogenetic protein 7 0.498 0.769 0.13
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.090 None 1.000 9 0 2016 2019