Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 50
Gene Symbol: ACO2
ACO2
aconitase 2 0.619 0.654 0.21
Malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 1983 1983
Entrez Id: 2175
Gene Symbol: FANCA
FANCA
FA complementation group A 0.505 0.731 1.6E-68
Malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 1983 1983
Entrez Id: 2184
Gene Symbol: FAH
FAH
fumarylacetoacetate hydrolase 0.612 0.538 4.0E-17
Malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 1983 1983
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
mutS homolog 6 0.462 0.731 3.7E-05
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.957 47 4 1988 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.378 0.885 8.0E-02
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 15 0 1988 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.979 48 0 1989 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.949 331 8 1990 2020
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.982 165 11 1990 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
CEA cell adhesion molecule 5 0.420 0.846 4.2E-10
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.984 122 0 1990 2020
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 12 0 1990 2019
Entrez Id: 4953
Gene Symbol: ODC1
ODC1
ornithine decarboxylase 1 0.510 0.731 0.17
Malignant neoplasm of colon and/or rectum
disease 0.090 None 1.000 9 1 1990 2011
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
sequestosome 1 0.428 0.885 8.6E-04
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 1990 2017
Entrez Id: 10657
Gene Symbol: KHDRBS1
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1 0.457 0.846 0.99
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 1990 2018
Entrez Id: 2965
Gene Symbol: GTF2H1
GTF2H1
general transcription factor IIH subunit 1 0.469 0.846 0.99
Malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 1990 2014
Entrez Id: 23636
Gene Symbol: NUP62
NUP62
nucleoporin 62 0.470 0.885 0.95
Malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 1990 2014
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
dynactin subunit 4 0.472 0.846 0.73
Malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 1990 2014
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1
serine peptidase inhibitor Kazal type 1 0.492 0.808 0.31
Malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 1990 1990
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.974 459 6 1991 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 37 0 1991 2019
Entrez Id: 4163
Gene Symbol: MCC
MCC
MCC regulator of WNT signaling pathway 0.568 0.731 4.7E-16
Malignant neoplasm of colon and/or rectum
disease 0.090 None 1.000 9 0 1991 2018
Entrez Id: 4830
Gene Symbol: NME1
NME1
NME/NM23 nucleoside diphosphate kinase 1 0.443 0.808 3.2E-03
Malignant neoplasm of colon and/or rectum
disease 0.090 None 1.000 9 0 1991 1996
Entrez Id: 1084
Gene Symbol: CEACAM3
CEACAM3
CEA cell adhesion molecule 3 0.494 0.731 1.1E-09
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.977 44 0 1992 2020
Entrez Id: 1087
Gene Symbol: CEACAM7
CEACAM7
CEA cell adhesion molecule 7 0.494 0.769 1.3E-07
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.977 44 0 1992 2020
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
pregnancy specific beta-1-glycoprotein 2 0.492 0.731 1.4E-30
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.977 43 0 1992 2020
Entrez Id: 1630
Gene Symbol: DCC
DCC
DCC netrin 1 receptor 0.471 0.808 0.99
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.920 25 2 1992 2017