| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.500 | None | 0.963 | 1 | 38 | 1994 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.410 | None | 1.000 | 1 | 11 | 2006 | 2016 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.700 | None | 0.949 | 1 | 7 | 1995 | 2016 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.430 | None | 1.000 | 1 | 10 | 2001 | 2017 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.440 | None | 1.000 | 1 | 2 | 2000 | 2016 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0.979 | 1 | 12 | 2003 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.120 | None | 1.000 | 1 | 2 | 2001 | 2016 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.110 | None | 0.500 | 1 | 3 | 2001 | 2016 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 2 | 2016 | 2016 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 3 | 2016 | 2016 | ||||||||
|
KIT proto-oncogene, receptor tyrosine kinase | 0.366 | 0.808 | 0.98 |
|
disease | 0.500 | None | 1.000 | 1 | 2 | 2009 | 2020 | ||||||||
|
enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.376 | 0.885 | 1.00 |
|
disease | 0.140 | None | 1.000 | 1 | 3 | 2015 | 2017 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.420 | None | 1.000 | 1 | 7 | 2013 | 2017 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.500 | None | 0.967 | 1 | 6 | 2001 | 2020 | ||||||||
|
cyclin dependent kinase 4 | 0.412 | 0.808 | 6.3E-02 |
|
disease | 0.500 | None | 1.000 | 1 | 2 | 1999 | 2016 | ||||||||
|
Raf-1 proto-oncogene, serine/threonine kinase | 0.418 | 0.885 | 0.85 |
|
disease | 0.440 | None | 1.000 | 1 | 1 | 2005 | 2016 | ||||||||
|
GNAS complex locus | 0.420 | 0.885 | 0.68 |
|
disease | 0.100 | None | 1.000 | 1 | 2 | 2016 | 2016 | ||||||||
|
isocitrate dehydrogenase (NADP(+)) 1 | 0.424 | 0.808 | 2.6E-12 |
|
disease | 0.100 | None | 1.000 | 1 | 2 | 2016 | 2016 | ||||||||
|
CREB binding protein | 0.428 | 0.808 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 2 | 2016 | 2016 | ||||||||
|
Rac family small GTPase 1 | 0.429 | 0.962 | 0.76 |
|
disease | 0.440 | None | 1.000 | 1 | 2 | 2014 | 2019 | ||||||||
|
mitogen-activated protein kinase kinase 1 | 0.439 | 0.846 | 0.90 |
|
disease | 0.400 | None | 1.000 | 1 | 6 | 2016 | 2016 | ||||||||
|
beta-2-microglobulin | 0.447 | 0.846 | 0.56 |
|
disease | 0.100 | None | 1.000 | 1 | 3 | 2016 | 2016 | ||||||||
|
F-box and WD repeat domain containing 7 | 0.465 | 0.808 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 5 | 2016 | 2016 | ||||||||
|
phosphoinositide-3-kinase regulatory subunit 1 | 0.477 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 2 | 2016 | 2016 | ||||||||
|
splicing factor 3b subunit 1 | 0.511 | 0.731 | 1.00 |
|
disease | 0.140 | None | 1.000 | 1 | 3 | 2013 | 2020 |