Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1950
Gene Symbol: EGF
EGF 		epidermal growth factor 0.357 0.923 8.5E-17
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.080 None 1.000 8 0 1988 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.100 None 0.982 222 5 1989 2020
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3 		nuclear receptor subfamily 1 group I member 3 0.448 0.846 3.5E-08
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.030 None 1.000 3 0 1990 2018
Entrez Id: 759
Gene Symbol: CA1
CA1 		carbonic anhydrase 1 0.623 0.769 4.7E-11
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 1990 1990
Entrez Id: 7157
Gene Symbol: TP53
TP53 		tumor protein p53 0.236 0.962 0.53
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.090 None 1.000 9 0 1992 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.070 None 1.000 7 0 1992 2015
Entrez Id: 960
Gene Symbol: CD44
CD44 		CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.050 None 1.000 5 0 1995 2011
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.100 None 1.000 12 0 1999 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		cadherin 1 0.401 0.808 0.15
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.020 None 1.000 2 0 1999 2011
Entrez Id: 51343
Gene Symbol: FZR1
FZR1 		fizzy and cell division cycle 20 related 1 0.670 0.538 1.00
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 1999 1999
Entrez Id: 5055
Gene Symbol: SERPINB2
SERPINB2 		serpin family B member 2 0.502 0.808 6.4E-12
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 1999 1999
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.090 None 1.000 9 0 2000 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		serine/threonine kinase 11 0.435 0.808 0.99
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.030 None 1.000 3 0 2000 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.100 None 0.990 102 0 2001 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.020 None 1.000 2 0 2001 2015
Entrez Id: 2736
Gene Symbol: GLI2
GLI2 		GLI family zinc finger 2 0.446 0.846 0.97
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 2001 2001
Entrez Id: 84105
Gene Symbol: PCBD2
PCBD2 		pterin-4 alpha-carbinolamine dehydratase 2 0.821 0.231 2.6E-02
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 2001 2001
Entrez Id: 168400
Gene Symbol: DDX53
DDX53 		DEAD-box helicase 53 0.568 0.846 0.66
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 2002 2002
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A 		5-hydroxytryptamine receptor 2A 0.473 0.846 0.51
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 2002 2002
Entrez Id: 80781
Gene Symbol: COL18A1
COL18A1 		collagen type XVIII alpha 1 chain 0.449 0.808 1.7E-10
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.030 None 1.000 3 0 2003 2014
Entrez Id: 1351
Gene Symbol: COX8A
COX8A 		cytochrome c oxidase subunit 8A 0.400 0.846 0.12
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 2003 2003
Entrez Id: 8754
Gene Symbol: ADAM9
ADAM9 		ADAM metallopeptidase domain 9 0.560 0.654 2.9E-02
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.040 None 1.000 4 0 2004 2017
Entrez Id: 1611
Gene Symbol: DAP
DAP 		death associated protein 0.530 0.808 3.5E-03
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.020 None 1.000 2 0 2004 2004
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.020 None 1.000 2 0 2004 2005
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		disease 0.010 None 1.000 1 0 2004 2004