Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
Secondary malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 2001 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 0.933 15 1 2001 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
Secondary malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 2 2016 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 69 0 2004 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
Secondary malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 1998 1998
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 0.971 35 1 2009 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 0.983 353 4 2003 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
Secondary malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 2016 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.020 None 1.000 2 0 2016 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 18 0 2007 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
Secondary malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 2006 2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
Secondary malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 2005 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
Secondary malignant neoplasm of colon and/or rectum
disease 0.050 None 1.000 5 0 2009 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.020 None 1.000 2 0 2005 2016
Entrez Id: 213
Gene Symbol: ALB
ALB
albumin 0.317 0.962 0.64
Secondary malignant neoplasm of colon and/or rectum
disease 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2012 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 0.993 145 2 2008 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 2014 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 0.980 492 4 2007 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
Secondary malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 2014 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 1 2013 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
Secondary malignant neoplasm of colon and/or rectum
disease 0.020 None 1.000 2 0 2017 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
Secondary malignant neoplasm of colon and/or rectum
disease 0.010 None 1.000 1 0 2013 2013
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
Secondary malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2017 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 2014 2019