Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.540 None 0.833 1 0 2011 2019
Entrez Id: 761
Gene Symbol: CA3
CA3
carbonic anhydrase 3 0.682 0.500 1.7E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.500 None 1.000 1 0 2014 2015
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
major histocompatibility complex, class I, B 0.379 0.885 3.9E-05
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 0.900 1 0 2009 2019
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6
cytochrome P450 family 2 subfamily B member 6 0.428 0.846 1.9E-10
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.380 None 0.889 1 0 2007 2018
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.333 0.923 1.1E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.370 None 1.000 1 0 2010 2019
Entrez Id: 2946
Gene Symbol: GSTM2
GSTM2
glutathione S-transferase mu 2 0.488 0.808 3.4E-07
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.350 None 1.000 1 0 2001 2014
Entrez Id: 335
Gene Symbol: APOA1
APOA1
apolipoprotein A1 0.429 0.885 5.5E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 2005 2017
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
high mobility group box 1 0.368 0.923 0.82
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 2009 2019
Entrez Id: 3875
Gene Symbol: KRT18
KRT18
keratin 18 0.530 0.692 0.73
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 1997 2017
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 1993 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2019
Entrez Id: 1647
Gene Symbol: GADD45A
GADD45A
growth arrest and DNA damage inducible alpha 0.526 0.769 4.4E-02
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2010 2014
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
ATP binding cassette subfamily C member 1 0.445 0.808 1.2E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2008 2020
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
secretory leukocyte peptidase inhibitor 0.449 0.846 9.0E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2007 2017
Entrez Id: 5444
Gene Symbol: PON1
PON1
paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2005 2019
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
C-X-C motif chemokine ligand 10 0.378 0.885 0.37
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2001 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2005 2012
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2015 2019
Entrez Id: 1373
Gene Symbol: CPS1
CPS1
carbamoyl-phosphate synthase 1 0.590 0.615 1.1E-09
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2015 2015
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1 0.407 0.885 8.9E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2015
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4
cytochrome P450 family 3 subfamily A member 4 0.462 0.885 5.8E-11
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2013 2018
Entrez Id: 196
Gene Symbol: AHR
AHR
aryl hydrocarbon receptor 0.410 0.923 1.00
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2017
Entrez Id: 2494
Gene Symbol: NR5A2
NR5A2
nuclear receptor subfamily 5 group A member 2 0.563 0.731 0.24
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2015 2018
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2
cytochrome P450 family 1 subfamily A member 2 0.494 0.923 2.5E-10
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2014 2018