| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
IgA nephropathy | 0.524 | 0.808 |
|
disease | 0.100 | None | 0.973 | 112 | 0 | 1980 | 2020 | |||||||||
|
immunoglobulin heavy constant alpha 1 | 0.617 | 0.692 |
|
disease | 0.100 | None | 0.982 | 109 | 0 | 1994 | 2020 | |||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.400 | None | 0.894 | 47 | 3 | 1995 | 2019 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.100 | None | 0.962 | 26 | 0 | 2000 | 2019 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.400 | None | 0.833 | 24 | 2 | 1993 | 2019 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.400 | None | 0.957 | 23 | 1 | 1995 | 2020 | ||||||||
|
complement factor H | 0.441 | 0.885 | 0.86 |
|
disease | 0.200 | None | 0.952 | 21 | 2 | 1991 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 1.000 | 19 | 0 | 1998 | 2019 | ||||||||
|
TNF superfamily member 13 | 0.499 | 0.769 | 0.82 |
|
disease | 0.500 | None | 1.000 | 15 | 1 | 2011 | 2020 | ||||||||
|
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.670 | 0.538 | 0.76 |
|
disease | 0.100 | None | 0.857 | 14 | 5 | 2005 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 1.000 | 14 | 1 | 1993 | 2020 | ||||||||
|
secretoglobin family 1A member 1 | 0.546 | 0.808 | 8.0E-04 |
|
disease | 0.300 | None | 0.929 | 14 | 0 | 1997 | 2007 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.300 | None | 1.000 | 12 | 0 | 2001 | 2018 | ||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
disease | 0.100 | None | 0.833 | 12 | 1 | 1997 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 1.000 | 11 | 1 | 1997 | 2018 | ||||||||
|
toll like receptor 9 | 0.411 | 0.885 | 9.8E-06 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2008 | 2020 | ||||||||
|
Fc fragment of IgA receptor | 0.666 | 0.538 | 6.6E-08 |
|
disease | 0.090 | None | 0.667 | 9 | 2 | 1997 | 2017 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.160 | None | 1.000 | 8 | 1 | 1999 | 2016 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 1994 | 2015 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.080 | None | 0.875 | 8 | 2 | 1994 | 2018 | ||||||||
|
serpin family B member 7 | 0.760 | 0.346 | 7.4E-09 |
|
disease | 0.080 | None | 0.875 | 8 | 2 | 1998 | 2016 | ||||||||
|
complement factor H related 3 | 0.663 | 0.462 | 1.7E-11 |
|
disease | 0.370 | None | 1.000 | 8 | 0 | 2011 | 2020 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2010 | 2018 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.070 | None | 1.000 | 7 | 3 | 2001 | 2017 | ||||||||
|
C1GALT1 specific chaperone 1 | 0.736 | 0.423 | 0.85 |
|
disease | 0.070 | None | 0.857 | 7 | 0 | 2005 | 2017 |