Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 GeneticVariation LHGDN Chronic myelocytic leukemia with eosinophilia, t(9;12)(q34;p13), and ETV6-ABL gene rearrangement: case report and review of the literature. 12505259

2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023418
Disease: leukemia
leukemia 		0.100 Biomarker LHGDN A dual inhibitor of PI3K and mTOR, PI-103, was more effective than rapamycin at suppressing proliferation of mouse pre-B-ALL and human CD19+CD34+)Ph+ ALL leukemia cells treated with the ABL kinase inhibitor imatinib. 18704194

2008
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 Biomarker LHGDN A masked BCR/ABL rearrangement in a case of chronic myeloid leukemia with translocation t(3;9)(p14;q34). 18262060

2008
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C1961102
Disease: Precursor Cell Lymphoblastic Leukemia Lymphoma
Precursor Cell Lymphoblastic Leukemia Lymphoma 		0.600 AlteredExpression LHGDN A new partner gene fused to ABL1 in a t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia. 17541395

2007
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 AlteredExpression LHGDN A novel BCR-ABL fusion transcript (e18a2) in a child with chronic myeloid leukemia. 17268511

2007
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0005699
Disease: Blast Phase
Blast Phase 		0.100 GeneticVariation LHGDN A point mutation leading to substitution at the ATP binding site of ABL-kinase and insensitivity to imatinib was detected in our patient treated with imatinib, who progressed to blast crisis. 12921956

2003
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C3714514
Disease: Infection
Infection 		0.030 AlteredExpression LHGDN Abelson tyrosine kinase facilitates Salmonella enterica serovar Typhimurium entry into epithelial cells. 18936177

2009
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 Biomarker LHGDN Abl: the prototype of oncogenic fusion proteins. 15583852

2004
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.010 GeneticVariation LHGDN aCGH local copy number aberrations associated with overall copy number genomic instability in colorectal cancer: coordinate involvement of the regions including BCR and ABL. 17196995

2007
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.030 AlteredExpression LHGDN Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells. 16410245

2006
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 Biomarker LHGDN Analysis and comparison of clinicohematological parameters and molecular and cytogenetic response of two Bcr/Abl fusion transcripts. 19048492

2008
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C3714514
Disease: Infection
Infection 		0.030 Biomarker LHGDN Anaplasma phagocytophilum AnkA secreted by type IV secretion system is tyrosine phosphorylated by Abl-1 to facilitate infection. 17587335

2007
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023470
Disease: Myeloid Leukemia
Myeloid Leukemia 		0.070 AlteredExpression LHGDN Assessment of bone marrow mesenchymal stem cell biological characteristics and support hemotopoiesis function in patients with chronic myeloid leukemia. 16448696

2006
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.040 GeneticVariation LHGDN Chronic myelocytic leukemia with eosinophilia, t(9;12)(q34;p13), and ETV6-ABL gene rearrangement: case report and review of the literature. 12505259

2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.100 Biomarker LHGDN Chronic myelogenous leukemia progenitors display a genetically unstable personality. 17470729

2007
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 GeneticVariation LHGDN Clinical outcome of 27 imatinib mesylate-resistant chronic myelogenous leukemia patients harboring a T315I BCR-ABL mutation. 17768119

2007
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 AlteredExpression LHGDN Clinical significance of dual color-dual fusion translocation fluorescence in situ hybridization in the detection of bcr/abl fusion gene. 12408765

2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023418
Disease: leukemia
leukemia 		0.100 AlteredExpression LHGDN Clinical significance of dual color-dual fusion translocation fluorescence in situ hybridization in the detection of bcr/abl fusion gene. 12408765

2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0032463
Disease: Polycythemia Vera
Polycythemia Vera 		0.100 AlteredExpression LHGDN Clinical significance of dual color-dual fusion translocation fluorescence in situ hybridization in the detection of bcr/abl fusion gene. 12408765

2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0032461
Disease: Polycythemia
Polycythemia 		0.020 AlteredExpression LHGDN Clinical significance of dual color-dual fusion translocation fluorescence in situ hybridization in the detection of bcr/abl fusion gene. 12408765

2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 GeneticVariation LHGDN Comprehensive comparison of FISH, RT-PCR, and RQ-PCR for monitoring the BCR-ABL gene after hematopoietic stem cell transplantation in CML. 12144533

2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C1961102
Disease: Precursor Cell Lymphoblastic Leukemia Lymphoma
Precursor Cell Lymphoblastic Leukemia Lymphoma 		0.600 Biomarker LHGDN Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia. 17761812

2007
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0026827
Disease: Muscle hypotonia
Muscle hypotonia 		0.010 GeneticVariation LHGDN Deletion in the ABL gene resulting from a meiotic recombination of a maternal (3;22;9)(q22;q12;q34.1) translocation. 12525554

2003
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.800 GeneticVariation LHGDN Deletions from the derivative chromosome 9, der(9), of the translocation, t(9;22)(q34;q11), at the site of the ABL/BCR fusion gene, have been demonstrated by fluorescence in situ hybridisation (FISH), in both Philadelphia chromosome (Ph)-positive chronic myeloid leukaemia (CML) and acute lymphoblastic leukaemia (ALL). 15716990

2005
Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C1961102
Disease: Precursor Cell Lymphoblastic Leukemia Lymphoma
Precursor Cell Lymphoblastic Leukemia Lymphoma 		0.600 GeneticVariation LHGDN Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia. 15716990

2005