×
Entrez Id: 761
Gene Symbol: CA3
CA3
Hepatitis, Drug-Induced
0.500
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249 2015
×
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Hepatitis, Drug-Induced
0.500
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750 2011
×
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Hepatitis, Drug-Induced
0.340
Biomarker
CTD_human
Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury.
28762043 2018
×
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Hepatitis, Drug-Induced
0.340
Biomarker
CTD_human
The aim of this study was to evaluate whether the polymorphism of the CYP2E1 gene is associated with antituberculosis drug-induced hepatitis .
12668988 2003
×
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Hepatitis, Drug-Induced
0.340
Biomarker
CTD_human
CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis.
16770646 2006
×
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Hepatitis, Drug-Induced
0.340
Biomarker
CTD_human
Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.
21741958 2011
×
Entrez Id: 10
Gene Symbol: NAT2
NAT2
Hepatitis, Drug-Induced
0.330
Biomarker
CTD_human
To determine whether acetylator status is a risk factor for antituberculosis drug-induced hepatitis , we genotyped NAT2 in 224 incident tuberculosis patients who received antituberculosis treatment.
11915035 2002
×
Entrez Id: 10
Gene Symbol: NAT2
NAT2
Hepatitis, Drug-Induced
0.330
Biomarker
CTD_human
Verified predominance of slow acetylator phenotype N-acetyltransferase 2 (NAT2) in a Hmong population residing in Minnesota.
16799928 2006
×
Entrez Id: 10
Gene Symbol: NAT2
NAT2
Hepatitis, Drug-Induced
0.330
Biomarker
CTD_human
Key factors of susceptibility to anti-tuberculosis drug-induced hepatotoxicity.
25693865 2015
×
Entrez Id: 10
Gene Symbol: NAT2
NAT2
Hepatitis, Drug-Induced
0.330
Biomarker
CTD_human
Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis.
17950035 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Hepatitis, Drug-Induced
0.310
Biomarker
CTD_human
Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure.
9696492 1998
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Hepatitis, Drug-Induced
0.310
Biomarker
CTD_human
Antioxidative roles of metallothionein and manganese superoxide dismutase induced by tumor necrosis factor-alpha and interleukin-6.
7532385 1995
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Hepatitis, Drug-Induced
0.310
Biomarker
CTD_human
Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha.
21984482 2012
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Hepatitis, Drug-Induced
0.310
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750 2011
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Hepatitis, Drug-Induced
0.310
Biomarker
CTD_human
Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity.
19638433 2009
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Hepatitis, Drug-Induced
0.310
Biomarker
CTD_human
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.
17709330 2007
×
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6
Hepatitis, Drug-Induced
0.310
Biomarker
CTD_human
Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury.
28762043 2018
×
Entrez Id: 51014
Gene Symbol: TMED7
TMED7
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
26881866 2016
MIRLET7B
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats.
30125006 2018
×
Entrez Id: 3727
Gene Symbol: JUND
JUND
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury.
30515189 2018
×
Entrez Id: 407037
Gene Symbol: MIR320A
MIR320A
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106 2017
×
Entrez Id: 3875
Gene Symbol: KRT18
KRT18
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo.
19783637 2009
×
Entrez Id: 406979
Gene Symbol: MIR19A
MIR19A
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis.
22363424 2012
×
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249 2015
×
Entrez Id: 100302197
Gene Symbol: MIR1306
MIR1306
Hepatitis, Drug-Induced
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106 2017