Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker PSYGENET Altogether, these findings suggest that these variants in the TIMELESS and RORA genes may confer susceptibility to BD and impact on circadian phenotypes in carriers who thus had lower ability to properly adapt to external cues. 24716566

2014

Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker PSYGENET Analysis of clock gene variants revealed that PER3 and RORA genotype predicted period lengthening by Li, whereas GSK3β genotype predicted rhythm effects of Li, specifically among BD cases. 24150227

2013

Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker PSYGENET The findings that have gained support indicate that genetic variants of RORA (rs2028122) and CRY1 (rs2287161) associate with depressive disorder, those of RORB (rs7022435, rs3750420, rs1157358, rs3903529) and NR1D1 (rs2314339) with bipolar disorder, and those of NPAS2 (rs11541353) and CRY2 (rs10838524) with seasonal affective disorder or winter depression. 22538398

2012

Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker PSYGENET Genetic and metabolic characterization of insomnia. 21494683

2011

Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker PSYGENET We examined 209 single-nucleotide polymorphisms (SNPs) covering 19 circadian genes (ADCYAP1, ARNTL, ARNTL2, BHLHB2, BHLHB3, CLOCK, CRY1, CRY2, CSNK1E, DBP, NPAS2, NR1D1, PER1, PER2, PER3, RORA, TIMELESS, VIP, and VIPR2) in a sample of 534 MD patients (335 with unipolar major mood depression (MDD) and 199 with bipolar disorder (BD)) and 440 community-based screened controls. 20072116

2010