Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Single nucleotide polymorphisms in the CRH receptor 1 (CRHR1) gene interact with ELS experience to predict depression as well as neuroendocrine and neuronal reactivity. 24931706

2014

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children. 25422957

2014

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Allelic variants of the glucocorticoid receptor (GR) gene contribute significantly to both cortisol levels and to measures of psychosis; corticotropin-releasing hormone receptor 1 variants contribute to measures of depression and psychosis. 24933348

2015

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Histone modifications of the Crhr1 gene in a rat model of depression following chronic stress. 24867333

2014

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Previous research supports gene-environment interactions for polymorphisms in the corticotropin hormone receptor 1 gene (CRHR1) and the serotonin transporter gene linked polymorphic region (5-HTTLPR) in predicting depression, but it has rarely considered genetic influences on stress sensitization processes, whereby early adversities (EA) increase depressive reactivity to proximal stressors later in life. 25422958

2014