Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.540 Biomarker PSYGENET This exploratory study provides an initial step for future studies to investigate an association between the reductions in SLC1A2 and GAD1 mRNA expression and their relation to the attenuation of the RAF/MEK/ERK signaling pathway in the dlPFC in MDD. 24652383

2015

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.540 Biomarker PSYGENET Prevalence statistics for past year and lifetime reports confirm differences between genders for CD, GAD, SAD, and MDD, and a lack of differences between twins and their non-twin siblings. 16465480

2006

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.540 Biomarker PSYGENET Subject to confirmation in an independent sample, our study suggests that variations in the GAD1 gene may contribute to individual differences in N and impact susceptibility across a range of anxiety disorders and major depression. 16718280

2006

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.540 Biomarker PSYGENET BPD subjects demonstrated significantly reduced PV mRNA, trend level reduction in SST mRNA and no alterations in GAD67, GAD65, or CR mRNA levels; MDD subjects demonstrated reduced SST mRNA expression without alterations in the other transcripts. 21226980

2011

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.540 Biomarker PSYGENET Our findings show abnormal BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders, indicating that fundamental properties of hippocampal signalling transmission, plasticity and circuitry may be affected in individuals with these major mental illnesses. 21223646

2011