Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.530 Biomarker PSYGENET BPD subjects demonstrated significantly reduced PV mRNA, trend level reduction in SST mRNA and no alterations in GAD67, GAD65, or CR mRNA levels; MDD subjects demonstrated reduced SST mRNA expression without alterations in the other transcripts. 21226980

2011

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.530 Biomarker PSYGENET Individuals with major depression also expressed significantly less GAD67 mRNA (44%) compared with controls in CA4 of the hippocampus. 21223646

2011

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.530 Biomarker PSYGENET Subject to confirmation in an independent sample, our study suggests that variations in the GAD1 gene may contribute to individual differences in N and impact susceptibility across a range of anxiety disorders and major depression. 16718280

2006

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.530 Biomarker PSYGENET This exploratory study provides an initial step for future studies to investigate an association between the reductions in SLC1A2 and GAD1 mRNA expression and their relation to the attenuation of the RAF/MEK/ERK signaling pathway in the dlPFC in MDD. 24652383

2014

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.530 Biomarker PSYGENET We report findings based on analyses of self-reports of six common adolescent psychopathologies (attention deficit/hyperactivity disorder, ADHD; conduct disorder, CD; oppositional defiant disorder, ODD; generalized anxiety disorder, GAD; separation anxiety disorder, SAD; and major depressive disorder, MDD) in a sample of 1,162 male and female adolescent (12-19 years) twin pairs and 426 siblings. 16465480

2006