| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ADAM metallopeptidase with thrombospondin type 1 motif 3 | 0.581 | 0.808 | 1.0E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
ADAM metallopeptidase with thrombospondin type 1 motif 4 | 0.582 | 0.692 | 2.0E-06 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
apolipoprotein A1 | 0.429 | 0.885 | 5.5E-04 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
arachidonate 5-lipoxygenase | 0.447 | 0.885 | 1.2E-06 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2018 | 2019 | ||||||||
|
ATP binding cassette subfamily G member 2 (Junior blood group) | 0.419 | 0.885 | 2.1E-32 |
|
disease | 0.120 | None | 1.000 | 2 | 1 | 2008 | 2019 | ||||||||
|
bromodomain containing 4 | 0.446 | 0.885 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 2006 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.020 | None | 0.500 | 2 | 2 | 2006 | 2016 | ||||||||
|
caspase 1 | 0.413 | 0.885 | 3.5E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
complement C5 | 0.550 | 0.731 | 8.1E-24 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
complement C5a receptor 1 | 0.513 | 0.808 | 0.40 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
glucokinase regulator | 0.604 | 0.615 | 8.5E-19 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2010 | 2019 | ||||||||
|
glycine receptor alpha 3 | 0.711 | 0.462 | 1.8E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
glycoprotein hormones, alpha polypeptide | 0.508 | 0.808 | 0.35 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
heat shock protein family A (Hsp70) member 14 | 0.502 | 0.769 | 0.67 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
heat shock protein family D (Hsp60) member 1 | 0.432 | 0.808 | 0.99 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
hypoxanthine phosphoribosyltransferase 1 | 0.500 | 0.808 | 0.94 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 1984 | 2016 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2016 | 2017 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 2013 | 2020 | ||||||||
|
interleukin 1 receptor type 1 | 0.509 | 0.769 | 0.15 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
LIF interleukin 6 family cytokine | 0.483 | 0.769 | 0.52 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
disease | 0.020 | None | 1.000 | 2 | 1 | 2014 | 2016 |