Source: CTD_mouse

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0234238
Disease: Ache
Ache 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 506
Gene Symbol: ATP5F1B
ATP5F1B
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker CTD_mouse Urinary ATP Synthase Subunit β Is a Novel Biomarker of Renal Mitochondrial Dysfunction in Acute Kidney Injury. 25666834

2015
Entrez Id: 506
Gene Symbol: ATP5F1B
ATP5F1B
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency 		0.500 Biomarker CTD_mouse Urinary ATP Synthase Subunit β Is a Novel Biomarker of Renal Mitochondrial Dysfunction in Acute Kidney Injury. 25666834

2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C1879321
Disease: Acute Myeloid Leukemia (AML-M2)
Acute Myeloid Leukemia (AML-M2) 		0.200 Biomarker CTD_mouse Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. 25822087

2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0026998
Disease: Acute Myeloid Leukemia, M1
Acute Myeloid Leukemia, M1 		0.200 Biomarker CTD_mouse Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. 25822087

2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.700 Biomarker CTD_mouse A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. 16247444

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.700 Biomarker CTD_mouse Overexpression of p53 protein, which is frequently demonstrated in virulent phenotypes of human corpus cancers, was seen in three out of eight (38%) adenocarcinomas, but not in the atypical hyperplasia or normal endometrial glands. 7955072

1994
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.400 Biomarker CTD_mouse DDR2(L63V);TP53(L/L) tumors displayed robust expression of DDR2 and immunohistochemical markers of lung adenocarcinoma comparable with previously generated models, though also displayed concomitant expression of the squamous cell markers p63 and SOX2. 26206333

2015
Entrez Id: 1678
Gene Symbol: TIMM8A
TIMM8A
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.260 Biomarker CTD_mouse c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. 27602772

2016
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.210 Biomarker CTD_mouse c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. 27602772

2016
Entrez Id: 2821
Gene Symbol: GPI
GPI
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.200 Biomarker CTD_mouse c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. 27602772

2016
Entrez Id: 8971
Gene Symbol: H1-10
H1-10
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.200 Biomarker CTD_mouse c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. 27602772

2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205641
Disease: Adenocarcinoma, Basal Cell
Adenocarcinoma, Basal Cell 		0.510 Biomarker CTD_mouse A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. 16247444

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205641
Disease: Adenocarcinoma, Basal Cell
Adenocarcinoma, Basal Cell 		0.510 Biomarker CTD_mouse Endometrial carcinogenesis induced by concurrent oral administration of ethylenethiourea and sodium nitrite in mice. 7955072

1994
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205642
Disease: Adenocarcinoma, Oxyphilic
Adenocarcinoma, Oxyphilic 		0.500 Biomarker CTD_mouse Endometrial carcinogenesis induced by concurrent oral administration of ethylenethiourea and sodium nitrite in mice. 7955072

1994
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205642
Disease: Adenocarcinoma, Oxyphilic
Adenocarcinoma, Oxyphilic 		0.500 Biomarker CTD_mouse A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. 16247444

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205645
Disease: Adenocarcinoma, Tubular
Adenocarcinoma, Tubular 		0.540 Biomarker CTD_mouse A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. 16247444

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205645
Disease: Adenocarcinoma, Tubular
Adenocarcinoma, Tubular 		0.540 Biomarker CTD_mouse Endometrial carcinogenesis induced by concurrent oral administration of ethylenethiourea and sodium nitrite in mice. 7955072

1994
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0041755
Disease: Adverse reaction to drug
Adverse reaction to drug 		0.500 Biomarker CTD_mouse Effects of serum lipoproteins on cyclosporine A cellular uptake and renal toxicity in vitro. 24502637

2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0041755
Disease: Adverse reaction to drug
Adverse reaction to drug 		0.500 Biomarker CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 7295
Gene Symbol: TXN
TXN
CUI: C0041755
Disease: Adverse reaction to drug
Adverse reaction to drug 		0.200 Therapeutic CTD_mouse Transgene expression of thioredoxin (TRX/ADF) protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced hematotoxicity. 11462148

2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0041755
Disease: Adverse reaction to drug
Adverse reaction to drug 		0.200 Biomarker CTD_mouse Methamphetamine-induced serotonin neurotoxicity is attenuated in p53-knockout mice. 9369336

1997
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0001925
Disease: Albuminuria
Albuminuria 		0.500 Biomarker CTD_mouse Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice. 29420703

2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.500 Biomarker CTD_mouse Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544

2011