| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.700 | None | 0.984 | 6 | 84 | 1982 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
group | 0.500 | None | 0.976 | 12 | 58 | 1976 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
group | 0.500 | None | 0.987 | 3 | 49 | 1995 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
group | 0.500 | None | 0.978 | 8 | 34 | 2004 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
group | 0.500 | None | 0.975 | 40 | 13 | 1987 | 2020 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
group | 0.450 | None | 1.000 | 4 | 7 | 1988 | 2016 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
group | 0.500 | None | 1.000 | 4 | 6 | 1998 | 2019 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
group | 0.500 | None | 0.978 | 14 | 5 | 1988 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
group | 0.500 | None | 0.964 | 4 | 5 | 2002 | 2017 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
group | 0.500 | None | 1.000 | 1 | 5 | 2006 | 2020 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
group | 0.500 | None | 1.000 | 1 | 5 | 2003 | 2019 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
group | 0.500 | None | 0.950 | 3 | 4 | 1991 | 2016 | ||||||||
|
F-box and WD repeat domain containing 7 | 0.465 | 0.808 | 1.00 |
|
group | 0.420 | None | 0.667 | 1 | 4 | 2008 | 2016 | ||||||||
|
erb-b2 receptor tyrosine kinase 3 | 0.448 | 0.808 | 1.7E-15 |
|
group | 0.500 | None | 1.000 | 2 | 3 | 1999 | 2018 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
group | 0.500 | None | 0.974 | 0 | 2 | 1996 | 2018 | ||||||||
|
mediator complex subunit 12 | 0.476 | 0.769 | 1.00 |
|
group | 0.430 | None | 1.000 | 2 | 1 | 2014 | 2016 | ||||||||
|
ALK receptor tyrosine kinase | 0.396 | 0.846 | 3.2E-06 |
|
group | 0.400 | None | 1.000 | 1 | 1 | 2016 | 2018 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
group | 0.450 | None | 1.000 | 0 | 1 | 2003 | 2008 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
group | 0.450 | None | 1.000 | 0 | 1 | 2004 | 2008 | ||||||||
|
CCCTC-binding factor | 0.504 | 0.769 | 1.00 |
|
group | 0.340 | None | 1.000 | 0 | 1 | 2003 | 2008 | ||||||||
|
transforming growth factor beta receptor 2 | 0.413 | 0.846 | 0.13 |
|
group | 0.340 | None | 1.000 | 0 | 1 | 2001 | 2008 | ||||||||
|
colony stimulating factor 3 | 0.377 | 0.885 | 0.38 |
|
group | 0.320 | None | 1.000 | 8 | 0 | 1993 | 2018 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
group | 0.400 | None | 0.988 | 6 | 0 | 1990 | 2019 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
group | 0.400 | None | 1.000 | 6 | 0 | 1992 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
group | 0.400 | None | 1.000 | 5 | 0 | 2001 | 2018 |