| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
RAD51 paralog B | 0.556 | 0.769 | 2.1E-15 |
|
disease | 0.500 | None | 0.913 | 1 | 57 | 2009 | 2019 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.500 | None | 0.943 | 3 | 14 | 1996 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.700 | None | 0.950 | 3 | 9 | 1994 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | None | 0.952 | 4 | 6 | 2001 | 2019 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.400 | None | 0.952 | 1 | 6 | 2000 | 2019 | ||||||||
|
mitogen-activated protein kinase kinase kinase 1 | 0.538 | 0.731 | 1.00 |
|
disease | 0.500 | None | 0.946 | 1 | 6 | 2007 | 2020 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.500 | None | 0.934 | 0 | 6 | 1996 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.700 | None | 0.955 | 12 | 5 | 1992 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.700 | None | 0.968 | 14 | 4 | 1981 | 2020 | ||||||||
|
protein regulator of cytokinesis 1 | 0.599 | 0.692 | 2.7E-07 |
|
disease | 0.470 | None | 1.000 | 1 | 4 | 2007 | 2018 | ||||||||
|
FTO alpha-ketoglutarate dependent dioxygenase | 0.486 | 0.885 | 8.4E-08 |
|
disease | 0.500 | None | 1.000 | 1 | 4 | 2011 | 2019 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.700 | None | 0.961 | 1 | 4 | 2007 | 2020 | ||||||||
|
lymphocyte specific protein 1 | 0.700 | 0.462 | 1.5E-06 |
|
disease | 0.500 | None | 1.000 | 2 | 3 | 2007 | 2017 | ||||||||
|
zinc finger protein 365 | 0.641 | 0.654 | 4.7E-04 |
|
disease | 0.500 | None | 1.000 | 1 | 3 | 2010 | 2017 | ||||||||
|
autophagy related 10 | 0.653 | 0.577 | 2.2E-08 |
|
disease | 0.420 | None | 1.000 | 1 | 3 | 2013 | 2018 | ||||||||
|
leucine rich repeat containing G protein-coupled receptor 6 | 0.502 | 0.923 | 2.9E-06 |
|
disease | 0.470 | None | 1.000 | 2 | 2 | 2008 | 2019 | ||||||||
|
SET binding protein 1 | 0.503 | 0.808 | 1.00 |
|
disease | 0.400 | None | 1.000 | 1 | 2 | 2015 | 2017 | ||||||||
|
MDM4 regulator of p53 | 0.461 | 0.808 | 1.00 |
|
disease | 0.500 | None | 0.953 | 1 | 2 | 1995 | 2019 | ||||||||
|
TOX high mobility group box family member 3 | 0.636 | 0.538 | 1.00 |
|
disease | 0.500 | None | 0.942 | 1 | 2 | 2007 | 2019 | ||||||||
|
zinc finger CCCH-type containing 11A | 0.821 | 0.154 | 1.00 |
|
disease | 0.410 | None | 1.000 | 1 | 2 | 2014 | 2017 | ||||||||
|
syntaxin binding protein 4 | 0.760 | 0.231 | 2.5E-14 |
|
disease | 0.450 | None | 1.000 | 1 | 2 | 2009 | 2019 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.500 | None | 0.966 | 6 | 1 | 1990 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.700 | None | 0.966 | 4 | 1 | 1997 | 2020 | ||||||||
|
caspase 8 | 0.404 | 0.923 | 3.7E-06 |
|
disease | 0.700 | None | 0.980 | 4 | 1 | 2004 | 2019 | ||||||||
|
L3MBTL histone methyl-lysine binding protein 3 | 0.700 | 0.423 | 1.00 |
|
disease | 0.400 | None | 1.000 | 1 | 1 | 2017 | 2018 |