×
Entrez Id:
10060
Gene Symbol:
ABCC9
ABCC9
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating.
15034580
2004
×
Entrez Id:
70
Gene Symbol:
ACTC1
ACTC1
Familial dilated cardiomyopathy
0.310
GermlineCausalMutation
ORPHANET
Actin mutations in dilated cardiomyopathy, a heritable form of heart failure.
9563954
1998
×
Entrez Id:
88
Gene Symbol:
ACTN2
ACTN2
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis.
14567970
2004
×
Entrez Id:
88
Gene Symbol:
ACTN2
ACTN2
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Exome sequencing identifies a mutation in the ACTN2 gene in a family with idiopathic ventricular fibrillation, left ventricular noncompaction, and sudden death.
25224718
2014
×
Entrez Id:
27063
Gene Symbol:
ANKRD1
ANKRD1
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Mutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathy.
19525294
2009
×
Entrez Id:
9531
Gene Symbol:
BAG3
BAG3
Familial dilated cardiomyopathy
0.430
GermlineCausalMutation
ORPHANET
Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy.
21353195
2011
×
Entrez Id:
10486
Gene Symbol:
CAP2
CAP2
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
CAP2 mutation leads to impaired actin dynamics and associates with supraventricular tachycardia and dilated cardiomyopathy.
30518548
2019
×
Entrez Id:
1410
Gene Symbol:
CRYAB
CRYAB
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Alpha B-crystallin mutation in dilated cardiomyopathy.
16483541
2006
×
Entrez Id:
1410
Gene Symbol:
CRYAB
CRYAB
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
alphaB-crystallin mutation in dilated cardiomyopathies: low prevalence in a consecutive series of 200 unrelated probands.
16793013
2006
×
Entrez Id:
8048
Gene Symbol:
CSRP3
CSRP3
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis.
14567970
2004
×
Entrez Id:
1674
Gene Symbol:
DES
DES
Familial dilated cardiomyopathy
0.330
GermlineCausalMutation
ORPHANET
Desmin mutation responsible for idiopathic dilated cardiomyopathy.
10430757
1999
×
Entrez Id:
1756
Gene Symbol:
DMD
DMD
Familial dilated cardiomyopathy
0.340
GermlineCausalMutation
ORPHANET
Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis.
14567970
2004
×
Entrez Id:
22845
Gene Symbol:
DOLK
DOLK
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Autosomal recessive dilated cardiomyopathy due to DOLK mutations results from abnormal dystroglycan O-mannosylation.
22242004
2011
×
Entrez Id:
1829
Gene Symbol:
DSG2
DSG2
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
To test whether perturbations of DSG2 or DSC2 exhibit a pathogenic impact on DCM pathogenesis, we sequenced both genes in 73 patients with FDCM and assessed prevalence of missense variations in matched control cohorts.
18678517
2008
×
Entrez Id:
2274
Gene Symbol:
FHL2
FHL2
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy.
17416352
2007
×
Entrez Id:
2218
Gene Symbol:
FKTN
FKTN
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness.
17036286
2006
×
Entrez Id:
57798
Gene Symbol:
GATAD1
GATAD1
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Homozygosity mapping and exome sequencing reveal GATAD1 mutation in autosomal recessive dilated cardiomyopathy.
21965549
2011
×
Entrez Id:
3910
Gene Symbol:
LAMA4
LAMA4
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells.
17646580
2007
×
Entrez Id:
11155
Gene Symbol:
LDB3
LDB3
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C.
14660611
2004
×
Entrez Id:
11155
Gene Symbol:
LDB3
LDB3
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction.
14662268
2003
×
Entrez Id:
4607
Gene Symbol:
MYBPC3
MYBPC3
Familial dilated cardiomyopathy
0.400
GermlineCausalMutation
ORPHANET
Coding sequence rare variants identified in MYBPC3, MYH6, TPM1, TNNC1, and TNNI3 from 312 patients with familial or idiopathic dilated cardiomyopathy.
20215591
2010
×
Entrez Id:
4624
Gene Symbol:
MYH6
MYH6
Familial dilated cardiomyopathy
0.400
GermlineCausalMutation
ORPHANET
Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy.
15998695
2005
×
Entrez Id:
4624
Gene Symbol:
MYH6
MYH6
Familial dilated cardiomyopathy
0.400
GermlineCausalMutation
ORPHANET
Coding sequence rare variants identified in MYBPC3, MYH6, TPM1, TNNC1, and TNNI3 from 312 patients with familial or idiopathic dilated cardiomyopathy.
20215591
2010
×
Entrez Id:
4625
Gene Symbol:
MYH7
MYH7
Familial dilated cardiomyopathy
0.410
GermlineCausalMutation
ORPHANET
Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy.
11106718
2000
×
Entrez Id:
84665
Gene Symbol:
MYPN
MYPN
Familial dilated cardiomyopathy
0.300
GermlineCausalMutation
ORPHANET
Novel mutations in the sarcomeric protein myopalladin in patients with dilated cardiomyopathy.
22892539
2013