Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5724
Gene Symbol: PTAFR
PTAFR
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Therapeutic RGD Mechanisms of glomerular injury in experimental immune nephritis. II. Effect of a platelet activating factor receptor antagonist in an autologous nephritis model. 1668710

1991

Entrez Id: 966
Gene Symbol: CD59
CD59
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD To assess the role of CD59 in complement-mediated glomerular injury, 6D1 was tested in a model of experimental glomerulonephritis induced by a lectin and its antibodies. 7523753

1994

Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Characterization of the mononuclear cell infiltrate in the glomerulus of rats with glomerulonephritis. 7538648

1995

Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Renal leukotriene C4 synthase: characterization, partial purification and alterations in experimental glomerulonephritis. 7827126

1995

Entrez Id: 246
Gene Symbol: ALOX15
ALOX15
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Co-regulated expression of glomerular 12/15-lipoxygenase and interleukin-4 mRNAs in rat nephrotoxic nephritis. 7967345

1994

Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Fibrinogen mediates platelet-polymorphonuclear leukocyte cooperation during immune-complex glomerulonephritis in rats. 8083378

1994

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.240 Biomarker RGD Differential regulation of glomerular gelatinase B (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in obese Zucker rats. 9300240

1997

Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication. 10432400

1999

Entrez Id: 6916
Gene Symbol: TBXAS1
TBXAS1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Effect of thromboxane A2 inhibition and antagonism on prostaglandin and leukotriene synthesis in glomerular immune injury. 10560941

1999

Entrez Id: 729
Gene Symbol: C6
C6
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD C5b-9 membrane attack complex mediates endothelial cell apoptosis in experimental glomerulonephritis. 10807586

2000

Entrez Id: 6346
Gene Symbol: CCL1
CCL1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.500 Biomarker RGD Effective methylprednisolone dose in experimental crescentic glomerulonephritis. 11157384

2001

Entrez Id: 6354
Gene Symbol: CCL7
CCL7
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.500 Biomarker RGD Effective methylprednisolone dose in experimental crescentic glomerulonephritis. 11157384

2001

Entrez Id: 1285
Gene Symbol: COL4A3
COL4A3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.340 Biomarker RGD Expression and characterization of recombinant rat alpha 3(IV)NC1 and its use in induction of experimental autoimmune glomerulonephritis. 11158397

2001

Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Localization of annexin V in rat normal kidney and experimental glomerulonephritis. 11271515

2001

Entrez Id: 2621
Gene Symbol: GAS6
GAS6
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD In the present study, therefore, we examined in vivo roles of Gas6 and Axl in an experimental model of mesangial proliferative glomerulonephritis induced by the injection of anti-Thy1.1 antibody (Thy1 GN). 11290560

2001

Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis. 11290560

2001

Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.220 Therapeutic RGD Rats with progressive mesangioproliferative glomerulonephritis were treated from day 3 to day 7 after disease induction with a high-affinity oligonucleotide aptamer antagonist against platelet-derived growth factor-B chain (PDGF-B). 11316849

2001

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.500 Therapeutic RGD Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats. 11318962

2001

Entrez Id: 2353
Gene Symbol: FOS
FOS
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD Retinoid receptor-specific agonists alleviate experimental glomerulonephritis. 11880336

2002

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.230 Biomarker RGD Involvement of dipeptidyl peptidase IV in immune complex-mediated glomerulonephritis. 11950907

2002

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.220 Biomarker RGD The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury. 12495295

2002

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury. 12495295

2002

Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. 12675855

2003

Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD This study investigated the potential of MCs to synthesize CX3CL1/fractalkine, a CX3C chemokine, both in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003

Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Expression of CX3CL1/fractalkine by mesangial cells in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003