Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5997
Gene Symbol: RGS2
RGS2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 SusceptibilityMutation RGD Impaired response of regulator of Gαq signaling-2 mRNA to angiotensin II and hypertensive renal injury in Dahl salt-sensitive rats. 26606876

2016

Entrez Id: 144100
Gene Symbol: PLEKHA7
PLEKHA7
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. 25136115

2014

Entrez Id: 55328
Gene Symbol: RNLS
RNLS
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Lisinopril protects against the adriamycin nephropathy and reverses the renalase reduction: potential role of renalase in adriamycin nephropathy. 24022426

2013

Entrez Id: 2702
Gene Symbol: GJA5
GJA5
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Cx40 was detected in mesangial cells in normal rat glomeruli; its expression was reduced on days 3 and 7 and recovered to normal on day 14 following GN induction. 22945766

2013

Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Production and degradation of extracellular matrix in reversible glomerular lesions in rat model of habu snake venom-induced glomerulonephritis. 23224597

2012

Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy. 20610530

2011

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Glomerulosclerosis was assessed by renal biopsy 8 wk later, and rats were divided into four groups with equivalent glomerulosclerosis: no further treatment, ARB, AT2 receptor antagonist, or combination. 20042458

2010

Entrez Id: 3675
Gene Symbol: ITGA3
ITGA3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Podocyte foot process effacement in very early phase of passive Heymann nephritis is not a prerequisite for proteinuria. 19662603

2009

Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Podocyte foot process effacement in very early phase of passive Heymann nephritis is not a prerequisite for proteinuria. 19662603

2009

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression. 19139720

2009

Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Anti-perforin antibody treatment ameliorates experimental crescentic glomerulonephritis in WKY rats. 17622272

2007

Entrez Id: 2200
Gene Symbol: FBN1
FBN1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD During the acute phase of experimental Thy1.1 nephritis, glomerular fibrillin-1 messenger ribonucleic acid expression and protein immunoreactivity were significantly induced as compared to controls. 16395273

2006

Entrez Id: 2200
Gene Symbol: FBN1
FBN1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD We hypothesized that LTBP-1 and fibrillin-1 are coexpressed in the glomerulus and upregulated during glomerulonephritis. 16282705

2006

Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Expression of allograft inflammatory factor-1 in kidneys: A novel molecular component of podocyte. 17035944

2006

Entrez Id: 4052
Gene Symbol: LTBP1
LTBP1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD We hypothesized that LTBP-1 and fibrillin-1 are coexpressed in the glomerulus and upregulated during glomerulonephritis. 16282705

2006

Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD These data suggest that the activation of STAT3 and Smad1 participates in the developing process of glomerulosclerosis in experimental glomerulonephritis. 15591053

2005

Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 ModifyingMutation RGD Increased 5-lipoxygenase activating protein in immune-mediated experimental nephritis. 14733414

2004

Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD This study investigated the potential of MCs to synthesize CX3CL1/fractalkine, a CX3C chemokine, both in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003

Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Expression of CX3CL1/fractalkine by mesangial cells in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury. 12495295

2002

Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis. 11290560

2001

Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Localization of annexin V in rat normal kidney and experimental glomerulonephritis. 11271515

2001

Entrez Id: 729
Gene Symbol: C6
C6
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD C5b-9 membrane attack complex mediates endothelial cell apoptosis in experimental glomerulonephritis. 10807586

2000

Entrez Id: 6916
Gene Symbol: TBXAS1
TBXAS1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Effect of thromboxane A2 inhibition and antagonism on prostaglandin and leukotriene synthesis in glomerular immune injury. 10560941

1999

Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication. 10432400

1999