Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.240 Biomarker RGD Podocyte repopulation contributes to regression of glomerular injury induced by ACE inhibition. 19164508

2009

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.240 Therapeutic RGD Inhibiting angiotensin-converting enzyme promotes renal repair by limiting progenitor cell proliferation and restoring the glomerular architecture. 21718676

2011

Entrez Id: 133
Gene Symbol: ADM
ADM
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.510 Biomarker RGD During GN a reduction of CLR and RAMP 2 + 3 expressions was detected on days 3, 7 and 14, while RAMP 1 rose.ADM mRNA decreased on days 3 and 7. 20431304

2010

Entrez Id: 133
Gene Symbol: ADM
ADM
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.510 Biomarker RGD Then, we made an anti-glomerular basement membrane (GBM) GN rat model and compared the AM expression and production in each glomeruli obtained from the control or m-PSL-treated anti-GBM GN rats. 16735801

2006

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 ModifyingMutation RGD Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats. 15888567

2005

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.220 Biomarker RGD The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury. 12495295

2002

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Glomerulosclerosis was assessed by renal biopsy 8 wk later, and rats were divided into four groups with equivalent glomerulosclerosis: no further treatment, ARB, AT2 receptor antagonist, or combination. 20042458

2010

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury. 12495295

2002

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression. 19139720

2009

Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Expression of allograft inflammatory factor-1 in kidneys: A novel molecular component of podocyte. 17035944

2006

Entrez Id: 246
Gene Symbol: ALOX15
ALOX15
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Co-regulated expression of glomerular 12/15-lipoxygenase and interleukin-4 mRNAs in rat nephrotoxic nephritis. 7967345

1994

Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 ModifyingMutation RGD Increased 5-lipoxygenase activating protein in immune-mediated experimental nephritis. 14733414

2004

Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Localization of annexin V in rat normal kidney and experimental glomerulonephritis. 11271515

2001

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD Less gelatinases is associated with apolipoprotein E accumulation in glomerulosclerosis rats. 22207560

2012

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD All-trans retinoic acid can regulate the expressions of gelatinases and apolipoprotein E in glomerulosclerosis rats. 21907828

2013

Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis. 11290560

2001

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.230 Biomarker RGD Involvement of dipeptidyl peptidase IV in immune complex-mediated glomerulonephritis. 11950907

2002

Entrez Id: 729
Gene Symbol: C6
C6
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD C5b-9 membrane attack complex mediates endothelial cell apoptosis in experimental glomerulonephritis. 10807586

2000

Entrez Id: 6346
Gene Symbol: CCL1
CCL1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.500 Biomarker RGD Effective methylprednisolone dose in experimental crescentic glomerulonephritis. 11157384

2001

Entrez Id: 6354
Gene Symbol: CCL7
CCL7
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.500 Biomarker RGD Effective methylprednisolone dose in experimental crescentic glomerulonephritis. 11157384

2001

Entrez Id: 966
Gene Symbol: CD59
CD59
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD To assess the role of CD59 in complement-mediated glomerular injury, 6D1 was tested in a model of experimental glomerulonephritis induced by a lectin and its antibodies. 7523753

1994

Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy. 20610530

2011

Entrez Id: 1285
Gene Symbol: COL4A3
COL4A3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.340 Biomarker RGD Expression and characterization of recombinant rat alpha 3(IV)NC1 and its use in induction of experimental autoimmune glomerulonephritis. 11158397

2001

Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD This study investigated the potential of MCs to synthesize CX3CL1/fractalkine, a CX3C chemokine, both in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003

Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication. 10432400

1999