Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker LHGDN Potential candidate genes in these regions that have been implicated in diabetic nephropathy and/or renal damage in models of hypertension include CYBA (or P22PHOX) (16q24), NOX1 (10q22), and NOX3 (6q25.1-q26). 17336700

2007

Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker LHGDN Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells. 18158642

2008

Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 GeneticVariation LHGDN Preliminary characterisation of the promoter of the human p22(phox) gene: identification of a new polymorphism associated with hypertension. 12729892

2003

Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 Biomarker LHGDN NADPH oxidase-mediated oxidative stress: genetic studies of the p22(phox) gene in hypertension. 16115038

2006

Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 AlteredExpression LHGDN Increased free radical production in hypertension due to increased expression of the NADPH oxidase subunit p22(phox) in lymphoblast cell lines. 11910303

2002

Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.600 GeneticVariation LHGDN A novel CYBA variant, the -675A/T polymorphism, is associated with essential hypertension. 17620958

2007