Source: BEFREE
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
complement factor H | 0.441 | 0.885 | 0.86 |
|
disease | 0.500 | None | 0.961 | 476 | 31 | 2005 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.400 | None | 0.971 | 173 | 12 | 2000 | 2020 | ||||||||
|
age-related maculopathy susceptibility 2 | 0.670 | 0.308 | 5.2E-04 |
|
disease | 0.700 | limited | 0.951 | 164 | 8 | 2005 | 2019 | ||||||||
|
HtrA serine peptidase 1 | 0.532 | 0.692 | 4.9E-04 |
|
disease | 0.500 | limited | 0.940 | 129 | 9 | 2006 | 2019 | ||||||||
|
ATP binding cassette subfamily A member 4 | 0.493 | 0.769 | 5.3E-48 |
|
disease | 0.700 | strong | 0.957 | 66 | 7 | 1997 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.500 | None | 0.902 | 60 | 4 | 1998 | 2019 | ||||||||
|
complement factor B | 0.532 | 0.769 | 4.7E-16 |
|
disease | 0.700 | limited | 0.966 | 52 | 11 | 2006 | 2019 | ||||||||
|
ribulose-5-phosphate-3-epimerase | 0.575 | 0.538 | 2.5E-04 |
|
disease | 0.100 | None | 0.970 | 33 | 2 | 2003 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.100 | None | 0.900 | 30 | 3 | 2006 | 2019 | ||||||||
|
adenosylmethionine decarboxylase 1 | 0.593 | 0.577 | 0.98 |
|
disease | 0.100 | None | 1.000 | 26 | 0 | 2007 | 2020 | ||||||||
|
ELOVL fatty acid elongase 4 | 0.601 | 0.577 | 0.83 |
|
disease | 0.200 | None | 0.962 | 26 | 1 | 2001 | 2019 | ||||||||
|
plexin A2 | 0.447 | 0.808 | 1.1E-06 |
|
disease | 0.100 | None | 1.000 | 24 | 1 | 2011 | 2020 | ||||||||
|
adenosylmethionine decarboxylase 1 pseudogene 2 | 0.608 | 0.538 |
|
disease | 0.100 | None | 1.000 | 24 | 0 | 2007 | 2020 | |||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.100 | None | 0.957 | 23 | 1 | 2007 | 2019 | ||||||||
|
complement C3 | 0.445 | 0.885 | 0.90 |
|
disease | 0.700 | limited | 1.000 | 23 | 12 | 2007 | 2020 | ||||||||
|
complement factor I | 0.569 | 0.731 | 3.5E-08 |
|
disease | 0.500 | None | 0.960 | 23 | 4 | 2009 | 2019 | ||||||||
|
C-X3-C motif chemokine receptor 1 | 0.457 | 0.885 | 6.1E-02 |
|
disease | 0.100 | None | 0.955 | 22 | 7 | 2004 | 2019 | ||||||||
|
TIMP metallopeptidase inhibitor 3 | 0.445 | 0.923 | 0.63 |
|
disease | 0.500 | None | 0.905 | 20 | 0 | 1997 | 2019 | ||||||||
|
peripherin 2 | 0.551 | 0.500 | 0.12 |
|
disease | 0.200 | None | 1.000 | 19 | 3 | 1993 | 2019 | ||||||||
|
serpin family F member 1 | 0.460 | 0.846 | 7.8E-08 |
|
disease | 0.100 | None | 1.000 | 17 | 3 | 2001 | 2018 | ||||||||
|
lipase C, hepatic type | 0.585 | 0.654 | 3.3E-07 |
|
disease | 0.200 | None | 0.882 | 16 | 1 | 2010 | 2019 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
disease | 0.100 | None | 1.000 | 16 | 0 | 2012 | 2020 | ||||||||
|
complement factor H related 3 | 0.663 | 0.462 | 1.7E-11 |
|
disease | 0.500 | moderate | 1.000 | 16 | 1 | 2006 | 2019 | ||||||||
|
EGF containing fibulin extracellular matrix protein 1 | 0.540 | 0.769 | 1.00 |
|
disease | 0.100 | None | 0.933 | 15 | 1 | 2002 | 2017 | ||||||||
|
ATP binding cassette subfamily A member 1 | 0.467 | 0.846 | 1.5E-13 |
|
disease | 0.200 | None | 0.938 | 15 | 1 | 2005 | 2019 |