Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.962 1455 23 1990 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.967 483 0 1997 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 None 0.920 364 3 1994 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.967 360 5 1986 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.977 347 0 1996 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.982 335 1 2000 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.989 283 0 2000 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.947 281 1 1997 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 None 0.959 268 3 1990 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.992 265 1 2000 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.992 260 1 2000 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.992 259 0 2000 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 None 0.971 245 4 1989 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.991 218 0 1984 2020
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
BRCA1 DNA repair associated 0.367 0.923 9.2E-29
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.976 208 2 1994 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.985 202 1 2001 2020
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.964 195 7 1990 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.989 174 1 1992 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.362 0.846 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.971 173 2 1994 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 None 0.924 157 4 2003 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.993 152 0 1995 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.973 146 2 1997 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 0.350 0.846
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.867 143 0 1995 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
cytochrome c oxidase subunit II 0.352 0.962
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.993 142 0 1999 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit 0.376 0.885 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.993 135 2 2004 2020