Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
CUI: C0003130
Disease: Anoxia
Anoxia
0.070 AlteredExpression LHGDN The present observations support that upregulation of HIF-1 alpha and its downstream targets GLUT1 and SDF-1 in colorectal adenomas and carcinomas may be due to hypoxia, in close interaction with an active phosphatidylinositol 3-kinases-AKT-mTOR pathway. 18351386

2008

Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
CUI: C0003130
Disease: Anoxia
Anoxia
0.070 AlteredExpression LHGDN Expression of GLUT-1 in psoriasis and the relationship between GLUT-1 upregulation induced by hypoxia and proliferation of keratinocyte growth. 18565734

2008

Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
CUI: C0003130
Disease: Anoxia
Anoxia
0.070 AlteredExpression LHGDN In vivo, basal membrane GLUT1 is upregulated over gestation, increased in diabetic pregnancy, and decreased in chronic hypoxia, while microvillous membrane GLUT1 is unaffected. 12583599

2002

Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
CUI: C0003130
Disease: Anoxia
Anoxia
0.070 Biomarker LHGDN Endogenous hypoxia markers: case not proven! 18290322

2008

Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
CUI: C0003130
Disease: Anoxia
Anoxia
0.070 AlteredExpression LHGDN In contrast to BeWo cells, hypoxia produced minimal increases in GLUT1 expression in explants; however, treatment with MG-132 did upregulate syncytial basal membrane GLUT1. 17442736

2007

Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
CUI: C0003130
Disease: Anoxia
Anoxia
0.070 AlteredExpression LHGDN Significant coexpression of GLUT-1, Bcl-xL, and Bax could point to cooperation of these regulatory proteins in elimination due to irreversible injury, adaptation to hypoxia, reduction of further damage, and survival of colorectal cancer cells. 17404017

2007

Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
CUI: C0003130
Disease: Anoxia
Anoxia
0.070 Biomarker LHGDN Recent studies have shown that GLUT1 and GLUT3 are both expressed in chondrocytes and their HIF-1alpha-mediated transcription may be dually stimulated in response to hypoxia and low glucose conditions which in turn promote anaerobic glycolysis in favor of oxidative phosphorylation. 16136514

2005