| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.800 | strong | 0.973 | 14 | 16 | 1993 | 2020 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.600 | strong | 0.974 | 12 | 32 | 1988 | 2020 | ||||||||
|
thymidylate synthetase | 0.425 | 0.846 | 0.72 |
|
disease | 0.400 | None | 0.979 | 11 | 0 | 1991 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.947 | 8 | 7 | 1989 | 2020 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.400 | None | 0.932 | 8 | 0 | 1996 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.976 | 8 | 5 | 2002 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.800 | strong | 0.972 | 7 | 16 | 1990 | 2020 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.979 | 6 | 0 | 1994 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.700 | None | 0.983 | 5 | 3 | 1997 | 2020 | ||||||||
|
dihydropyrimidine dehydrogenase | 0.493 | 0.846 | 3.4E-22 |
|
disease | 0.400 | None | 0.965 | 5 | 0 | 1998 | 2020 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.800 | strong | 0.971 | 5 | 11 | 1993 | 2020 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.700 | strong | 0.981 | 3 | 3 | 1996 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.600 | None | 0.963 | 3 | 4 | 1990 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway 2 | 0.582 | 0.654 | 1.00 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 2008 | 2019 | ||||||||
|
glycoprotein nmb | 0.566 | 0.692 | 2.9E-27 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2008 | 2018 | ||||||||
|
secreted frizzled related protein 1 | 0.479 | 0.846 | 0.96 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2002 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.985 | 2 | 11 | 2002 | 2020 | ||||||||
|
thymidine phosphorylase | 0.495 | 0.769 | 1.2E-04 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 1996 | 2019 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.370 | None | 1.000 | 2 | 0 | 2000 | 2017 | ||||||||
|
protein tyrosine phosphatase receptor type D | 0.584 | 0.731 | 1.00 |
|
disease | 0.500 | None | 1.000 | 2 | 1 | 2008 | 2011 | ||||||||
|
toll like receptor 2 | 0.361 | 0.923 | 1.0E-06 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2006 | 2019 | ||||||||
|
guanylate cyclase 1 soluble subunit alpha 2 | 0.792 | 0.192 | 0.31 |
|
disease | 0.500 | None | 1.000 | 2 | 0 | 2008 | 2011 | ||||||||
|
cytochrome c oxidase subunit I | 0.441 | 0.885 |
|
disease | 0.500 | None | 1.000 | 2 | 2 | 1994 | 2019 | |||||||||
|
transcription factor 7 like 2 | 0.485 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.925 | 2 | 2 | 1999 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.700 | None | 1.000 | 2 | 3 | 1992 | 2019 |