Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human Effects of Neonicotinoid Pesticides on Promoter-Specific Aromatase (CYP19) Expression in Hs578t Breast Cancer Cells and the Role of the VEGF Pathway. 29701941

2018
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human Effects of Neonicotinoid Pesticides on Promoter-Specific Aromatase (CYP19) Expression in Hs578t Breast Cancer Cells and the Role of the VEGF Pathway. 29701941

2018
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer. 28112739

2017
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer. 28112739

2017
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human Associations between aromatase CYP19 rs10046 polymorphism and breast cancer risk: from a case-control to a meta-analysis of 20,098 subjects. 23342035

2013
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human Associations between aromatase CYP19 rs10046 polymorphism and breast cancer risk: from a case-control to a meta-analysis of 20,098 subjects. 23342035

2013
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.300 Biomarker CTD_human Relaxin and castration in male mice protect from, but testosterone exacerbates, age-related cardiac and renal fibrosis, whereas estrogens are an independent determinant of organ size. 22028442

2012
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C1136382
Disease: Sclerocystic Ovaries
Sclerocystic Ovaries 		0.300 Biomarker CTD_human The expression of sex steroid synthesis and inactivation enzymes in subcutaneous adipose tissue of PCOS patients. 22381227

2012
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C1623038
Disease: Cirrhosis
Cirrhosis 		0.300 Biomarker CTD_human Relaxin and castration in male mice protect from, but testosterone exacerbates, age-related cardiac and renal fibrosis, whereas estrogens are an independent determinant of organ size. 22028442

2012
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.300 Biomarker CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0205641
Disease: Adenocarcinoma, Basal Cell
Adenocarcinoma, Basal Cell 		0.300 Biomarker CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0205642
Disease: Adenocarcinoma, Oxyphilic
Adenocarcinoma, Oxyphilic 		0.300 Biomarker CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0205643
Disease: Carcinoma, Cribriform
Carcinoma, Cribriform 		0.300 Biomarker CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0205644
Disease: Carcinoma, Granular Cell
Carcinoma, Granular Cell 		0.300 Biomarker CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0205645
Disease: Adenocarcinoma, Tubular
Adenocarcinoma, Tubular 		0.300 Biomarker CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.300 Biomarker CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C1136382
Disease: Sclerocystic Ovaries
Sclerocystic Ovaries 		0.300 Biomarker CTD_human Alterations of folliculogenesis in women with polycystic ovary syndrome. 21262361

2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0029459
Disease: Osteoporosis, Senile
Osteoporosis, Senile 		0.300 Biomarker CTD_human Evaluation of a bioluminescent mouse model expressing aromatase PII-promoter-controlled luciferase as a tool for the study of endocrine disrupting chemicals. 20723554

2010
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0751406
Disease: Post-Traumatic Osteoporosis
Post-Traumatic Osteoporosis 		0.300 Biomarker CTD_human Evaluation of a bioluminescent mouse model expressing aromatase PII-promoter-controlled luciferase as a tool for the study of endocrine disrupting chemicals. 20723554

2010
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human The association between genetic polymorphisms in CYP19 and breast cancer risk in Korean women. 19639193

2009
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human The association between genetic polymorphisms in CYP19 and breast cancer risk in Korean women. 19639193

2009
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0038279
Disease: Sterility, Postpartum
Sterility, Postpartum 		0.300 Biomarker CTD_human Aromatase-knockout mouse carrying an estrogen-inducible enhanced green fluorescent protein gene facilitates detection of estrogen actions in vivo. 14684609

2004
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0341869
Disease: Subfertility, Female
Subfertility, Female 		0.300 Biomarker CTD_human Aromatase-knockout mouse carrying an estrogen-inducible enhanced green fluorescent protein gene facilitates detection of estrogen actions in vivo. 14684609

2004
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0917730
Disease: Female sterility
Female sterility 		0.300 Biomarker CTD_human Aromatase-knockout mouse carrying an estrogen-inducible enhanced green fluorescent protein gene facilitates detection of estrogen actions in vivo. 14684609

2004
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0020635
Disease: Hypopituitarism
Hypopituitarism 		0.300 Biomarker CTD_human Congenital hypopituitarism as a cause of undetectable estriol levels in the maternal triple-marker screen. 12970278

2003