×
Entrez Id: 539
Gene Symbol: ATP5PO
ATP5PO
Hypothyroidism
0.200
Therapeutic
RGD
3,5-diiodo-L-thyronine upregulates rat-liver mitochondrial F(o)F(1)-ATP synthase by GA-binding protein/nuclear respiratory factor-2.
19878644 2010
×
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
Hypothyroidism
0.200
Biomarker
RGD
5,10-Methylenetetrahydrofolate reductase levels are elevated in hyperthyroidism and decreased in hypothyroidism , whereas methionine synthase levels are decreased in hyperthyroidism and increased in hypothyroidism .
7990714 1994
×
Entrez Id: 4504
Gene Symbol: MT3
MT3
Hypothyroidism
0.200
Biomarker
RGD
Hypothyroidism was induced in pregnant dams by the administration of PTU from gestational day 7, resulting in a 4- to 6-fold increase in pup MT-3 mRNA abundance on the day of birth (day 0) and on postnatal day 3.10407136 1999
×
Entrez Id: 4537
Gene Symbol: ND3
ND3
Hypothyroidism
0.200
Biomarker
RGD
Hypothyroidism decreases ND3 mRNA levels in several brain areas such as cortex and hippocampus during the early postnatal development.7763274 1995
×
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
Hypothyroidism
0.210
Therapeutic
RGD
Pnpla3 mRNA decreased in WAT of hypothyroid rats and was partially restored by treatment with TH.19619606 2009
×
Entrez Id: 2934
Gene Symbol: GSN
GSN
Hypothyroidism
0.200
Biomarker
RGD
Gelsolin immunoreactivity and development of the tectorial membrane in the cochlea of normal and hypothyroid rats.2848627 1988
×
Entrez Id: 4131
Gene Symbol: MAP1B
MAP1B
Hypothyroidism
0.200
Biomarker
RGD
Microtubule-associated protein 1B but not 1A was still present in parallel fibres in less mature folia at P30 in hypothyroid rats suggesting that the expression of these two microtubule-associated proteins is regulated separately.3252178 1988
×
Entrez Id: 7038
Gene Symbol: TG
TG
Hypothyroidism
0.400
Biomarker
RGD
A novel missense mutation (G2320R) in thyroglobulin causes hypothyroidism in rdw rats.
11089535 2000
×
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1
Hypothyroidism
0.200
Biomarker
RGD
Cellular colocalization and coregulation between hypothalamic pro-TRH and prohormone convertases in hypothyroidism.
16926379 2007
×
Entrez Id: 4624
Gene Symbol: MYH6
MYH6
Hypothyroidism
0.200
Biomarker
RGD
Changes in myosin and creatine kinase mRNA levels with cardiac hypertrophy and hypothyroidism.
1703406 1991
×
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
Hypothyroidism
0.200
Biomarker
RGD
Changes in myosin and creatine kinase mRNA levels with cardiac hypertrophy and hypothyroidism.
1703406 1991
×
Entrez Id: 2695
Gene Symbol: GIP
GIP
Hypothyroidism
0.200
Biomarker
RGD
Conversely, GIP levels at 60 and 90 minutes following glucose ingestion in PTU-induced hypothyroid rats were higher than those in euthyroid rats.
9030821 1997
×
Entrez Id: 7352
Gene Symbol: UCP3
UCP3
Hypothyroidism
0.210
Biomarker
RGD
Conversely, chronic hypothyroidism results in a hypothermic response to MDMA that is directly proportionate to decreased UCP3 expression.
17012607 2007
×
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
Hypothyroidism
0.210
Therapeutic
RGD
Declined translated products of SOD1 and SOD2 in cerebellum of PTU-treated rats were alleviated on administration of curcumin to hypothyroid rats.
22076484 2012
×
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
Hypothyroidism
0.210
Biomarker
RGD
Decreased SOD1 and SOD2 activities in hypothyroid rats compared to control were either unaltered or further decreased in response to the antioxidants.
21607622 2012
×
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
Hypothyroidism
0.200
Biomarker
RGD
Decreased activity of lecithin:cholesterol acyltransferase and hepatic lipase in chronic hypothyroid rats: implications for reverse cholesterol transport.
12841343 2003
×
Entrez Id: 8851
Gene Symbol: CDK5R1
CDK5R1
Hypothyroidism
0.200
Biomarker
RGD
Developmental hypothyroidism induced by iodine deficiency and PTU treatment could delay the maturation of newborn granule neurons in dentate gyrus, and this deficit may be attributed to the downregulation of p35 .
22987596 2014
×
Entrez Id: 9572
Gene Symbol: NR1D1
NR1D1
Hypothyroidism
0.230
Biomarker
RGD
Developmental expression of mRNAs from a rat C-erbA genomic locus.
1315530 1992
×
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
Hypothyroidism
0.210
Biomarker
RGD
Developmental iodine deficiency and hypothyroidism impair neural development in rat hippocampus: involvement of doublecortin and NCAM-180.
20412599 2010
×
Entrez Id: 8985
Gene Symbol: PLOD3
PLOD3
Hypothyroidism
0.200
Biomarker
RGD
Differential expression of procollagen lysine 2-oxoglutarate 5-deoxygenase and matrix metalloproteinase isoforms in hypothyroid rat ovary and disintegration of extracellular matrix.
15817667 2005
×
Entrez Id: 4803
Gene Symbol: NGF
NGF
Hypothyroidism
0.200
Biomarker
RGD
Effects of postnatal thyroid hormone deficiency on neurogenesis in the juvenile and adult rat.
19233274 2009
×
Entrez Id: 89780
Gene Symbol: WNT3A
WNT3A
Hypothyroidism
0.200
Biomarker
RGD
Effects of postnatal thyroid hormone deficiency on neurogenesis in the juvenile and adult rat.
19233274 2009
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Hypothyroidism
0.310
Biomarker
RGD
Effects of triiodothyronine and propylthiouracil on plasma lipoproteins in male rats.
6816881 1982
×
Entrez Id: 210
Gene Symbol: ALAD
ALAD
Hypothyroidism
0.210
Biomarker
RGD
Experimental hypothyroidism inhibits delta-aminolevulinate dehydratase activity in neonatal rat blood and liver.
17720948 2007
×
Entrez Id: 6469
Gene Symbol: SHH
SHH
Hypothyroidism
0.300
Biomarker
RGD
Expression of sonic hedgehog regulates morphological changes of rat developing cerebellum in hypothyroidism.
18827446 2008