| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
CF transmembrane conductance regulator | 0.424 | 0.885 | 2.2E-58 |
|
disease | 1.000 | None | 0.979 | 2327 | 632 | 1989 | 2020 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.100 | None | 0.962 | 80 | 3 | 1992 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.970 | 33 | 0 | 1993 | 2019 | ||||||||
|
elastase, neutrophil expressed | 0.447 | 0.846 | 1.2E-03 |
|
disease | 0.100 | None | 0.962 | 26 | 0 | 1992 | 2019 | ||||||||
|
spermine oxidase | 0.603 | 0.769 | 0.40 |
|
disease | 0.100 | None | 0.880 | 25 | 0 | 1990 | 2019 | ||||||||
|
serpin family A member 1 | 0.410 | 0.923 | 6.8E-08 |
|
disease | 0.200 | None | 0.957 | 23 | 1 | 1991 | 2019 | ||||||||
|
mannose binding lectin 2 | 0.390 | 0.846 | 2.7E-03 |
|
disease | 0.200 | None | 0.913 | 23 | 2 | 1999 | 2019 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.100 | None | 1.000 | 18 | 0 | 1986 | 1990 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 1.000 | 18 | 2 | 1996 | 2019 | ||||||||
|
sodium channel epithelial 1 subunit beta | 0.628 | 0.577 | 5.8E-08 |
|
disease | 0.600 | None | 1.000 | 17 | 0 | 2005 | 2019 | ||||||||
|
FEV transcription factor, ETS family member | 0.593 | 0.692 | 8.1E-03 |
|
disease | 0.100 | None | 0.875 | 16 | 0 | 2000 | 2018 | ||||||||
|
anoctamin 1 | 0.516 | 0.769 | 0.87 |
|
disease | 0.100 | None | 1.000 | 15 | 0 | 2011 | 2020 | ||||||||
|
deoxyribonuclease 1 | 0.505 | 0.846 | 7.0E-21 |
|
disease | 0.100 | None | 0.929 | 14 | 0 | 1990 | 2019 | ||||||||
|
mucin 5B, oligomeric mucus/gel-forming | 0.532 | 0.808 | 1.00 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 1998 | 2019 | ||||||||
|
mucin 5AC, oligomeric mucus/gel-forming | 0.483 | 0.808 | 1.0E-08 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1998 | 2019 | ||||||||
|
solute carrier family 9 member A6 | 0.516 | 0.846 | 1.00 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 2009 | 2020 | ||||||||
|
sodium channel epithelial 1 subunit alpha | 0.601 | 0.577 | 1.1E-11 |
|
disease | 0.390 | None | 0.909 | 11 | 1 | 2004 | 2017 | ||||||||
|
solute carrier family 26 member 9 | 0.743 | 0.423 | 1.3E-02 |
|
disease | 0.100 | None | 1.000 | 11 | 1 | 2013 | 2020 | ||||||||
|
myeloperoxidase | 0.377 | 0.923 | 7.1E-15 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1996 | 2019 | ||||||||
|
nitric oxide synthase 2 | 0.364 | 0.923 | 4.0E-15 |
|
disease | 0.100 | None | 0.909 | 11 | 0 | 1998 | 2019 | ||||||||
|
Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 2007 | 2020 | |||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 2000 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 1999 | 2019 | ||||||||
|
ATP binding cassette subfamily B member 6 (Langereis blood group) | 0.431 | 0.885 | 8.6E-19 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2001 | 2019 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 1992 | 2008 |