Source: BEFREE
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PR/SET domain 1 | 0.538 | 0.731 | 0.96 |
|
disease | 0.550 | None | 1.000 | 5 | 0 | 2009 | 2017 | ||||||||
|
DEF6 guanine nucleotide exchange factor | 0.751 | 0.346 | 1.00 |
|
disease | 0.520 | None | 1.000 | 2 | 0 | 2006 | 2018 | ||||||||
|
Fc fragment of IgG receptor IIa | 0.480 | 0.769 | 2.0E-06 |
|
disease | 0.500 | None | 0.906 | 28 | 1 | 1995 | 2019 | ||||||||
|
major histocompatibility complex, class II, DQ alpha 1 | 0.416 | 0.846 | 2.4E-02 |
|
disease | 0.500 | None | 0.931 | 23 | 0 | 1991 | 2016 | ||||||||
|
secreted phosphoprotein 1 | 0.353 | 0.885 | 2.1E-06 |
|
disease | 0.500 | None | 0.952 | 20 | 3 | 1998 | 2019 | ||||||||
|
methyl-CpG binding protein 2 | 0.414 | 0.846 | 0.89 |
|
disease | 0.500 | None | 1.000 | 13 | 6 | 2008 | 2018 | ||||||||
|
interleukin 1 receptor associated kinase 1 | 0.506 | 0.808 | 0.99 |
|
disease | 0.500 | None | 1.000 | 11 | 3 | 2007 | 2019 | ||||||||
|
ubiquitin conjugating enzyme E2 L3 | 0.644 | 0.615 | 0.84 |
|
disease | 0.490 | None | 0.941 | 9 | 1 | 2008 | 2020 | ||||||||
|
deoxyribonuclease 1 like 3 | 0.575 | 0.769 | 3.0E-05 |
|
disease | 0.470 | None | 1.000 | 7 | 0 | 2011 | 2020 | ||||||||
|
PHD and ring finger domains 1 | 0.743 | 0.346 | 5.7E-02 |
|
disease | 0.470 | None | 0.875 | 7 | 2 | 2008 | 2012 | ||||||||
|
complement C2 | 0.617 | 0.692 | 1.3E-16 |
|
disease | 0.450 | strong | 1.000 | 5 | 0 | 1976 | 2015 | ||||||||
|
solute carrier family 15 member 4 | 0.805 | 0.269 | 1.9E-06 |
|
disease | 0.440 | None | 1.000 | 4 | 7 | 2009 | 2017 | ||||||||
|
UHRF1 binding protein 1 | 0.769 | 0.269 | 4.5E-13 |
|
disease | 0.430 | None | 0.857 | 3 | 2 | 2009 | 2019 | ||||||||
|
C-type lectin domain containing 16A | 0.612 | 0.654 | 0.28 |
|
disease | 0.410 | None | 1.000 | 1 | 1 | 2009 | 2017 | ||||||||
|
RAS guanyl releasing protein 3 | 0.686 | 0.500 | 9.1E-03 |
|
disease | 0.410 | None | 1.000 | 1 | 1 | 2009 | 2017 | ||||||||
|
complement C1r | 0.638 | 0.654 | 0.78 |
|
disease | 0.410 | strong | 1.000 | 1 | 0 | 2011 | 2017 | ||||||||
|
KIAA0319 like | 0.711 | 0.423 | 1.2E-03 |
|
disease | 0.410 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.952 | 81 | 3 | 1990 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.400 | None | 0.923 | 51 | 3 | 1987 | 2020 | ||||||||
|
Fc fragment of IgG receptor IIIb | 0.452 | 0.962 | 3.0E-07 |
|
disease | 0.400 | None | 0.925 | 38 | 2 | 1999 | 2019 | ||||||||
|
interleukin 21 | 0.441 | 0.769 | 0.63 |
|
disease | 0.400 | None | 1.000 | 36 | 3 | 2004 | 2019 | ||||||||
|
Fas cell surface death receptor | 0.372 | 0.923 | 0.81 |
|
disease | 0.400 | None | 0.943 | 24 | 2 | 1978 | 2020 | ||||||||
|
prolactin | 0.406 | 0.885 | 2.9E-07 |
|
disease | 0.400 | None | 0.963 | 24 | 1 | 1997 | 2019 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
disease | 0.400 | None | 0.895 | 19 | 1 | 1996 | 2018 | ||||||||
|
toll like receptor 5 | 0.518 | 0.885 | 2.5E-13 |
|
disease | 0.400 | None | 0.882 | 17 | 1 | 2001 | 2019 |