Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2214
Gene Symbol: FCGR3A
FCGR3A
Fc fragment of IgG receptor IIIa 0.432 0.962 3.7E-06
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.846 39 5 1998 2019
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
programmed cell death 1 0.402 0.846 0.42
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.800 None 0.949 39 2 1998 2020
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
RNA binding motif protein 45 0.383 0.846 2.1E-10
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.973 37 0 1992 2018
Entrez Id: 59067
Gene Symbol: IL21
IL21
interleukin 21 0.441 0.769 0.63
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.400 None 1.000 37 3 2004 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.972 36 0 1995 2019
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.400 None 0.943 35 2 1978 2020
Entrez Id: 50616
Gene Symbol: IL22
IL22
interleukin 22 0.393 0.885 1.9E-04
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 1.000 33 1 2004 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.969 32 3 1996 2019
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A
Fc fragment of IgG receptor IIa 0.480 0.769 2.0E-06
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.500 None 0.906 32 3 1995 2019
Entrez Id: 3606
Gene Symbol: IL18
IL18
interleukin 18 0.365 0.923 3.1E-02
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.969 32 4 2002 2019
Entrez Id: 11277
Gene Symbol: TREX1
TREX1
three prime repair exonuclease 1 0.517 0.808 0.58
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.800 strong 0.967 30 10 2007 2020
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
forkhead box P3 0.368 0.846 0.99
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.933 30 0 2005 2020
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 1.000 30 0 1988 2019
Entrez Id: 7292
Gene Symbol: TNFSF4
TNFSF4
TNF superfamily member 4 0.540 0.808 4.9E-02
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.600 None 0.967 30 17 2008 2019
Entrez Id: 919
Gene Symbol: CD247
CD247
CD247 molecule 0.539 0.731 1.7E-02
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.200 None 1.000 30 2 1998 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.862 29 2 1998 2020
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1 0.416 0.846 2.4E-02
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.500 None 0.931 29 2 1991 2016
Entrez Id: 718
Gene Symbol: C3
C3
complement C3 0.445 0.885 0.90
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.200 None 0.897 29 3 1981 2020
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.897 29 8 2000 2019
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
DNA methyltransferase 1 0.406 0.885 1.00
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.857 28 0 2004 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.100 None 0.893 28 0 2001 2020
Entrez Id: 6738
Gene Symbol: RO60
RO60
Ro60, Y RNA binding protein 0.610 0.692 0.58
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.300 None 0.929 28 0 1987 2019
Entrez Id: 10318
Gene Symbol: TNIP1
TNIP1
TNFAIP3 interacting protein 1 0.564 0.769 0.48
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.700 None 0.926 27 6 2009 2019
Entrez Id: 5617
Gene Symbol: PRL
PRL
prolactin 0.406 0.885 2.9E-07
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.400 None 0.963 27 1 1997 2019
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
interleukin 2 receptor subunit alpha 0.389 0.885 5.5E-02
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.200 None 0.923 26 2 1992 2019