Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3980
Gene Symbol: LIG3
LIG3
DNA ligase 3 0.641 0.654 1.4E-10
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 3948
Gene Symbol: LDHC
LDHC
lactate dehydrogenase C 0.711 0.500 5.3E-07
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2006 2006
Entrez Id: 3939
Gene Symbol: LDHA
LDHA
lactate dehydrogenase A 0.507 0.808 6.9E-02
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2006 2006
Entrez Id: 384
Gene Symbol: ARG2
ARG2
arginase 2 0.569 0.731 1.8E-04
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2013 2013
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
Janus kinase 1 0.474 0.769 1.00
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
microRNA 203a 0.471 0.808
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
microRNA 221 0.449 0.846
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.401 0.808 1.00
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
nuclear factor of activated T cells 2 0.525 0.731 1.00
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 2 2014 2014
Entrez Id: 4512
Gene Symbol: COX1
COX1
cytochrome c oxidase subunit I 0.441 0.885
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2015 2015
Entrez Id: 4287
Gene Symbol: ATXN3
ATXN3
ataxin 3 0.521 0.808 0.11
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2007 2007
Entrez Id: 4240
Gene Symbol: MFGE8
MFGE8
milk fat globule-EGF factor 8 protein 0.548 0.808 4.4E-05
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 4162
Gene Symbol: MCAM
MCAM
melanoma cell adhesion molecule 0.514 0.731 1.6E-04
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2012 2012
Entrez Id: 410
Gene Symbol: ARSA
ARSA
arylsulfatase A 0.448 0.923 1.1E-11
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
integrin subunit beta 2 0.444 0.923 5.1E-15
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2002 2002
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2007 2007
Entrez Id: 969
Gene Symbol: CD69
CD69
CD69 molecule 0.488 0.923 3.0E-02
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 84106
Gene Symbol: PRAM1
PRAM1
PML-RARA regulated adaptor molecule 1 0.700 0.462 3.0E-04
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2002 2002
Entrez Id: 83667
Gene Symbol: SESN2
SESN2
sestrin 2 0.508 0.808 4.2E-07
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2012 2012
Entrez Id: 81890
Gene Symbol: QTRT1
QTRT1
queuine tRNA-ribosyltransferase catalytic subunit 1 0.659 0.538 2.6E-07
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 8170
Gene Symbol: SLC14A2
SLC14A2
solute carrier family 14 member 2 0.606 0.692 1.1E-17
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2013 2013
Entrez Id: 81608
Gene Symbol: FIP1L1
FIP1L1
factor interacting with PAPOLA and CPSF1 0.575 0.577 0.79
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential
disease 0.010 None 1.000 1 0 2007 2007