| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
MDM2 proto-oncogene | 0.362 | 0.846 | 1.00 |
|
disease | 0.100 | None | 0.972 | 32 | 3 | 1993 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 32 | 0 | 2002 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.100 | None | 1.000 | 32 | 0 | 2002 | 2019 | ||||||||
|
notch receptor 1 | 0.369 | 0.885 | 1.00 |
|
disease | 0.600 | None | 0.935 | 30 | 0 | 2007 | 2019 | ||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
disease | 0.100 | None | 0.966 | 29 | 0 | 1998 | 2018 | |||||||||
|
MT-CO2 pseudogene 12 | 0.368 | 0.962 |
|
disease | 0.100 | None | 0.963 | 27 | 0 | 1998 | 2018 | |||||||||
|
cytochrome P450 family 1 subfamily A member 1 | 0.436 | 0.846 | 1.1E-17 |
|
disease | 0.100 | None | 1.000 | 27 | 1 | 1994 | 2016 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.400 | None | 1.000 | 27 | 2 | 2002 | 2019 | ||||||||
|
ALK receptor tyrosine kinase | 0.396 | 0.846 | 3.2E-06 |
|
disease | 0.100 | None | 0.926 | 27 | 0 | 2008 | 2019 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.100 | None | 0.967 | 27 | 2 | 2003 | 2019 | ||||||||
|
Ras association domain family member 1 | 0.420 | 0.808 | 4.9E-06 |
|
disease | 0.100 | None | 0.966 | 26 | 0 | 2002 | 2018 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.400 | None | 0.971 | 25 | 1 | 2001 | 2019 | ||||||||
|
podoplanin | 0.470 | 0.769 | 3.2E-04 |
|
disease | 0.100 | None | 1.000 | 24 | 0 | 2005 | 2019 | ||||||||
|
NK2 homeobox 1 | 0.457 | 0.808 | 0.36 |
|
disease | 0.100 | None | 0.917 | 24 | 0 | 2002 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.958 | 23 | 2 | 1994 | 2019 | ||||||||
|
fibroblast growth factor receptor 1 | 0.362 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.917 | 22 | 0 | 2008 | 2018 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.400 | None | 0.917 | 22 | 1 | 1997 | 2019 | ||||||||
|
microRNA 21 | 0.363 | 0.846 |
|
disease | 0.100 | None | 0.955 | 21 | 0 | 2008 | 2018 | |||||||||
|
O-6-methylguanine-DNA methyltransferase | 0.412 | 0.885 | 1.2E-07 |
|
disease | 0.100 | None | 1.000 | 21 | 0 | 2001 | 2018 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.100 | None | 0.955 | 21 | 2 | 2003 | 2019 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.400 | None | 0.962 | 20 | 1 | 2001 | 2020 | ||||||||
|
glutathione S-transferase theta 1 | 0.393 | 0.923 | 1.5E-04 |
|
disease | 0.100 | None | 0.955 | 19 | 0 | 1994 | 2014 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.400 | None | 0.957 | 19 | 1 | 1999 | 2019 | ||||||||
|
proliferating cell nuclear antigen | 0.382 | 0.846 | 0.98 |
|
disease | 0.100 | None | 1.000 | 19 | 0 | 1994 | 2019 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.400 | None | 1.000 | 19 | 0 | 1994 | 2018 |