Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD ET(A)-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat. 11179039

2001

Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.270 Biomarker RGD This is the first report showing that the expression of p22-phox and gp91-phox, essential components of NADPH oxidase, are increased in the infarcted sites after myocardial infarction. 11243862

2001

Entrez Id: 3371
Gene Symbol: TNC
TNC
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.250 Biomarker RGD We examined the expression of TNC after experimental myocardial infarction in the rat by immunohistochemistry and in situ hybridization. 11454990

2001

Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.240 Biomarker RGD This is the first report showing that the expression of p22-phox and gp91-phox, essential components of NADPH oxidase, are increased in the infarcted sites after myocardial infarction. 11243862

2001

Entrez Id: 3033
Gene Symbol: HADH
HADH
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Serial evaluation of fatty acid metabolism in rats with myocardial infarction by pinhole SPECT. 11481570

2001

Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.320 Biomarker RGD Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats. 12123772

2002

Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Potent adenylate cyclase agonist forskolin restores myoprotective effects of ischemic preconditioning in rat hearts after myocardial infarction. 12400771

2002

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD We, therefore, examined the expression and localization of HO-1 in a rat experimental myocardial infarction model. 12392996

2002

Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796

2002

Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796

2002

Entrez Id: 1605
Gene Symbol: DAG1
DAG1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Therapeutic RGD Myocardial regeneration therapy for heart failure: hepatocyte growth factor enhances the effect of cellular cardiomyoplasty. 12034665

2002

Entrez Id: 7273
Gene Symbol: TTN
TTN
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD In a rat model of ischemia-induced myocardial infarction (left anterior descending coronary artery ligature), 43% of animals, but only 14% of sham-operated animals, showed a distinct N2BA titin band on gels. 12221049

2002

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.540 Biomarker RGD Antioxidant enzyme gene expression in congestive heart failure following myocardial infarction. 14575298

2003

Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.520 Biomarker RGD Antioxidant enzyme gene expression in congestive heart failure following myocardial infarction. 14575298

2003

Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.230 Biomarker RGD Endothelin-1 receptor subtypes expression and binding in a perfused rat model of myocardial infarction. 12524016

2003

Entrez Id: 4282
Gene Symbol: MIF
MIF
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.220 Biomarker RGD Expression of macrophage migration inhibitory factor in acute ischemic myocardial injury. 12704210

2003

Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Results of ET-1 binding affinity post-MI indicated drastic reduction in spite the upregulation of ET(B) on coronary endothelium. 12524016

2003

Entrez Id: 859
Gene Symbol: CAV3
CAV3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Caveolin-1 and -3 dissociations from caveolae to cytosol in the heart during aging and after myocardial infarction in rat. 12566108

2003

Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Effect of propranolol on cardiac cytokine expression after myocardial infarction in rats. 14575314

2003

Entrez Id: 4985
Gene Symbol: OPRD1
OPRD1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels. 12798419

2003

Entrez Id: 4625
Gene Symbol: MYH7
MYH7
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.500 Biomarker RGD Differential gene expression in infarct scar and viable myocardium from rat heart following coronary ligation. 15090263

2004

Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cells of ischemic myocardium. 15247145

2004

Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Thus, myocardial ischemia induced by left coronary artery ligation resulted in a sustained increase in Ang-2 expression and a reciprocal decrease in Ang-1, consistent with a predominant role for Ang-2 in the angiogenic response to MI. 15364619

2004

Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.250 Biomarker RGD In vivo transfer of soluble TNF-alpha receptor 1 gene improves cardiac function and reduces infarct size after myocardial infarction in rats. 15117889

2004

Entrez Id: 10911
Gene Symbol: UTS2
UTS2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.220 Biomarker RGD Urotensin-II-mediated cardiomyocyte hypertrophy: effect of receptor antagonism and role of inflammatory mediators. 15549273

2004