Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796

2002

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.520 Therapeutic RGD Myocardial autophagy variation during acute myocardial infarction in rats: the effects of carvedilol. 20079142

2009

Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Angiogenic signal triggered by ischemic stress induces myocardial repair in rat during chronic infarction. 15081314

2004

Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD The key findings of the present study were: a) upregulation of autophagy-related genes (GABARAPL1, ATG7, BNIP3, CTSL1 and LAMP2) was observed only in plantaris while muscle atrophy was observed in both soleus and plantaris muscles, and b) Cathepsin L activity, Bnip3 and Fis1 protein levels, and levels of lipid hydroperoxides were increased specifically in plantaris muscle of MI rats. 24427319

2014

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.250 Biomarker RGD Anti-ischemia/reperfusion of C1 inhibitor in myocardial cell injury via regulation of local myocardial C3 activity. 16996480

2006

Entrez Id: 730
Gene Symbol: C7
C7
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Time course studies on the initiation of complement activation in acute myocardial infarction induced by coronary artery ligation in rats. 15724448

2005

Entrez Id: 731
Gene Symbol: C8A
C8A
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. 7515561

1994

Entrez Id: 732
Gene Symbol: C8B
C8B
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. 7515561

1994

Entrez Id: 27101
Gene Symbol: CACYBP
CACYBP
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD We found that CacyBP/SIP was upregulated during myocardial infarction (MI) and hypoxia/reoxygenation. 16440310

2006

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Therapeutic RGD Ad-HGF improves the cardiac remodeling of rat following myocardial infarction by upregulating autophagy and necroptosis and inhibiting apoptosis. 27904666

2016

Entrez Id: 846
Gene Symbol: CASR
CASR
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.230 Biomarker RGD Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats. 22527939

2012

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.540 Biomarker RGD Antioxidant enzyme gene expression in congestive heart failure following myocardial infarction. 14575298

2003

Entrez Id: 859
Gene Symbol: CAV3
CAV3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Caveolin-1 and -3 dissociations from caveolae to cytosol in the heart during aging and after myocardial infarction in rat. 12566108

2003

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Therapeutic RGD In post-MI heart failure, ARB attenuated MCP-1 expression and macrophage infiltration in the border zone, resulting in less myocardial fibrosis. 18753699

2008

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Atorvastatin enhances interleukin-10 levels and improves cardiac function in rats after acute myocardial infarction. 18459941

2009

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.240 Biomarker RGD CCR3- and CXCR4-mediated interactions regulate migration of CD34+ human bone marrow progenitors to ischemic myocardium and subsequent tissue repair. 18954648

2008

Entrez Id: 1490
Gene Symbol: CCN2
CCN2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker RGD Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation. 18167060

2008

Entrez Id: 890
Gene Symbol: CCNA2
CCNA2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Acute myocardial infarction induced functional cardiomyocytes to re-enter the cell cycle. 23634243

2013

Entrez Id: 1232
Gene Symbol: CCR3
CCR3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD CCR3- and CXCR4-mediated interactions regulate migration of CD34+ human bone marrow progenitors to ischemic myocardium and subsequent tissue repair. 18954648

2008

Entrez Id: 948
Gene Symbol: CD36
CD36
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.250 ModifyingMutation RGD It can be concluded that transgenic expression of Cd36 plays an important role in modulating the incidence and severity of ischemic and reperfusion ventricular arrhythmias and myocardial infarct size induced by coronary artery occlusion. 22128087

2012

Entrez Id: 966
Gene Symbol: CD59
CD59
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.240 Biomarker RGD Loss of CD59 in the AMI lesions was observed in association with deposits of MAC from day one onward. 7515561

1994

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.230 Therapeutic RGD Post-myocardial infarct p27 fusion protein intravenous delivery averts adverse remodelling and improves heart function and survival in rodents. 22492676

2012

Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Therapeutic RGD Membrane ERα attenuates myocardial fibrosis via RhoA/ROCK-mediated actin remodeling in ovariectomized female infarcted rats. 24292258

2014

Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Therapeutic RGD microRNA-29b Mediates the Antifibrotic Effect of Tanshinone IIA in Postinfarct Cardiac Remodeling. 25636075

2015

Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.220 Therapeutic RGD microRNA-29b Mediates the Antifibrotic Effect of Tanshinone IIA in Postinfarct Cardiac Remodeling. 25636075

2015