|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Hepatoblastoma in a Noonan syndrome patient with a PTPN11 mutation.
|
18253957 |
2008 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Noonan, Costello and cardio-facio-cutaneous syndromes: dysregulation of the Ras-MAPK pathway.
|
19063751 |
2008 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Analysis of the PTPN11 gene in idiopathic short stature children and Noonan syndrome patients.
|
18331608 |
2008 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
[Phenotype variability in Noonan syndrome patients with and without PTPN11 mutation].
|
17546245 |
2007 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
The role of Shp2 (PTPN11) in cancer.
|
17227708 |
2007 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Mutational analysis of PTPN11 gene in Taiwanese children with Noonan syndrome.
|
17339163 |
2007 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Noonan syndrome.
|
17222357 |
2007 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects.
|
16377799 |
2006 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Transgenic Drosophila models of Noonan syndrome causing PTPN11 gain-of-function mutations.
|
16399795 |
2006 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
PTPN11 gene analysis in 74 Brazilian patients with Noonan syndrome or Noonan-like phenotype.
|
17020470 |
2006 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease.
|
16358218 |
2006 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Neurofibromatosis-Noonan syndrome: molecular evidence of the concurrence of both disorders in a patient.
|
15948193 |
2005 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes.
|
15987685 |
2005 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Genotypic and phenotypic characterization of Noonan syndrome: new data and review of the literature.
|
15723289 |
2005 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Acquired PTPN11 mutations occur rarely in adult patients with myelodysplastic syndromes and chronic myelomonocytic leukemia.
|
15725481 |
2005 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
A novel mutation in the PTPN11 gene in a patient with Noonan syndrome and rapidly progressive hypertrophic cardiomyopathy.
|
15889278 |
2005 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
SHP-2 and myeloid malignancies.
|
14676626 |
2004 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
PTPN11 mutations in pediatric patients with acute myeloid leukemia: results from the Children's Cancer Group.
|
15385933 |
2004 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Genetics and variation in phenotype in Noonan syndrome.
|
15539800 |
2004 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis.
|
14644997 |
2004 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation.
|
14974085 |
2004 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia.
|
12717436 |
2003 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
PTPN11 (protein-tyrosine phosphatase, nonreceptor-type 11) mutations in seven Japanese patients with Noonan syndrome.
|
12161469 |
2002 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Grouping of multiple-lentigines/LEOPARD and Noonan syndromes on the PTPN11 gene.
|
12058348 |
2002 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Noonan Syndrome 1
|
0.910 |
CausalMutation |
CLINVAR |
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome.
|
11704759 |
2001 |