Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.985 202 1 2001 2020
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.964 195 7 1990 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.989 174 1 1992 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.362 0.846 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.971 173 2 1994 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.993 152 0 1995 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.973 146 2 1997 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 0.350 0.846
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.867 143 0 1995 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
cytochrome c oxidase subunit II 0.352 0.962
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.993 142 0 1999 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit 0.376 0.885 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.993 135 2 2004 2020
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 0.368 0.962
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.993 134 0 1999 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.948 134 1 1990 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.970 133 0 1992 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.992 129 1 1999 2020
Entrez Id: 367
Gene Symbol: AR
AR
androgen receptor 0.351 0.846 0.99
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.968 125 0 1997 2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 0.363 0.846
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.991 107 0 2006 2019
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
Yes associated protein 1 0.432 0.808 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.990 98 0 2007 2020
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
GA binding protein transcription factor subunit alpha 0.379 0.885 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.979 97 0 2005 2020
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.884 95 1 1987 2020
Entrez Id: 1950
Gene Symbol: EGF
EGF
epidermal growth factor 0.357 0.923 8.5E-17
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.989 94 2 1990 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.401 0.808 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.989 94 0 1996 2020
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.926 94 1 1996 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.989 92 1 1989 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.989 91 0 1994 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 1.000 90 0 2005 2020
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
menin 1 0.444 0.808 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 None 0.922 90 0 1991 2020