| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.500 | None | 0.859 | 3 | 1 | 1997 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.600 | None | 0.780 | 1 | 0 | 1995 | 2019 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.530 | None | 1.000 | 1 | 0 | 2011 | 2019 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.500 | None | 0.750 | 4 | 1 | 2006 | 2019 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 1999 | 2016 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.400 | None | 0.932 | 4 | 0 | 1998 | 2020 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2005 | 2019 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
toll like receptor 2 | 0.361 | 0.923 | 1.0E-06 |
|
disease | 0.310 | None | 0.500 | 2 | 0 | 2013 | 2015 | ||||||||
|
fibroblast growth factor receptor 1 | 0.362 | 0.885 | 1.00 |
|
disease | 0.420 | None | 1.000 | 1 | 1 | 2006 | 2017 | ||||||||
|
intercellular adhesion molecule 1 | 0.364 | 0.962 | 3.5E-02 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2005 | 2018 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
disease | 0.360 | None | 0.500 | 2 | 0 | 2008 | 2018 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
cytotoxic T-lymphocyte associated protein 4 | 0.369 | 0.923 | 0.94 |
|
disease | 0.340 | None | 1.000 | 3 | 0 | 2002 | 2015 | ||||||||
|
major histocompatibility complex, class I, A | 0.370 | 0.846 | 1.3E-03 |
|
disease | 0.470 | None | 0.500 | 4 | 8 | 2002 | 2019 | ||||||||
|
Fas cell surface death receptor | 0.372 | 0.923 | 0.81 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.320 | None | 1.000 | 1 | 0 | 2008 | 2013 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.330 | None | 0.500 | 2 | 0 | 2011 | 2019 | ||||||||
|
kinase insert domain receptor | 0.378 | 0.885 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2016 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.400 | None | 0.250 | 4 | 0 | 2003 | 2015 | ||||||||
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
disease | 0.430 | None | 1.000 | 2 | 9 | 2006 | 2019 | ||||||||
|
mitogen-activated protein kinase 3 | 0.379 | 0.885 | 3.7E-02 |
|
disease | 0.340 | None | 1.000 | 2 | 0 | 2008 | 2017 | ||||||||
|
mitogen-activated protein kinase 14 | 0.379 | 0.923 | 0.37 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2008 | 2017 | ||||||||
|
glutathione S-transferase mu 1 | 0.380 | 0.923 | 2.1E-03 |
|
disease | 0.390 | None | 0.750 | 4 | 0 | 2001 | 2016 |