Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Effect of exogenous kappa-opioid receptor activation in rat model of myocardial infarction. 15076225

2004

Entrez Id: 1460
Gene Symbol: CSNK2B
CSNK2B
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Differential gene expression in infarct scar and viable myocardium from rat heart following coronary ligation. 15090263

2004

Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Effect of propranolol on cardiac cytokine expression after myocardial infarction in rats. 14575314

2003

Entrez Id: 4985
Gene Symbol: OPRD1
OPRD1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels. 12798419

2003

Entrez Id: 1605
Gene Symbol: DAG1
DAG1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Therapeutic RGD Myocardial regeneration therapy for heart failure: hepatocyte growth factor enhances the effect of cellular cardiomyoplasty. 12034665

2002

Entrez Id: 7273
Gene Symbol: TTN
TTN
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD In a rat model of ischemia-induced myocardial infarction (left anterior descending coronary artery ligature), 43% of animals, but only 14% of sham-operated animals, showed a distinct N2BA titin band on gels. 12221049

2002

Entrez Id: 3033
Gene Symbol: HADH
HADH
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Serial evaluation of fatty acid metabolism in rats with myocardial infarction by pinhole SPECT. 11481570

2001

Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Identification of regulated genes in rat heart after myocardial infarction by means of differential mRNA display. 10807530

2000

Entrez Id: 1907
Gene Symbol: EDN2
EDN2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo. 10573185

1999

Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Elevation of expression of Smads 2, 3, and 4, decorin and TGF-beta in the chronic phase of myocardial infarct scar healing. 10198196

1999

Entrez Id: 5331
Gene Symbol: PLCB3
PLCB3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Expression of Gq alpha and PLC-beta in scar and border tissue in heart failure due to myocardial infarction. 9521338

1998

Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Expression of Gq alpha and PLC-beta in scar and border tissue in heart failure due to myocardial infarction. 9521338

1998

Entrez Id: 2535
Gene Symbol: FZD2
FZD2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD A homologue of Drosophila tissue polarity gene frizzled is expressed in migrating myofibroblasts in the infarcted rat heart. 9142123

1997

Entrez Id: 731
Gene Symbol: C8A
C8A
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. 7515561

1994

Entrez Id: 732
Gene Symbol: C8B
C8B
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. 7515561

1994

Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Therapeutic RGD Integrin β1 Increases Stem Cell Survival and Cardiac Function after Myocardial Infarction. 28367125

2017

Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Transient Receptor Potential Vanilloid 1 Regulates Mitochondrial Membrane Potential and Myocardial Reperfusion Injury. 27671317

2016

Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD The key findings of the present study were: a) upregulation of autophagy-related genes (GABARAPL1, ATG7, BNIP3, CTSL1 and LAMP2) was observed only in plantaris while muscle atrophy was observed in both soleus and plantaris muscles, and b) Cathepsin L activity, Bnip3 and Fis1 protein levels, and levels of lipid hydroperoxides were increased specifically in plantaris muscle of MI rats. 24427319

2014

Entrez Id: 4208
Gene Symbol: MEF2C
MEF2C
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Therapeutic RGD Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling. 23948075

2013

Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD TREK-1 demonstrates specific changes in expression and electrophysiological function in left ventricle post MI. 21683547

2012

Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Therapeutic RGD Expression of mitochondrial fusion-fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition. 20886221

2011

Entrez Id: 7035
Gene Symbol: TFPI
TFPI
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Therapeutic RGD Treatment with irbesartan plus carvedilol reduced the expression of TF and TFPI mRNA and protein after MI in rats, and combined treatment with both agents had greater effects than the single agents alone. 21229253

2011

Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Hepcidin is strongly induced in cardiomyocytes under myocarditis and MI, conditions in which inflammatory cytokine levels increase and may play an important role in iron homeostasis and free radical generation. 19615879

2010

Entrez Id: 84557
Gene Symbol: MAP1LC3A
MAP1LC3A
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Therapeutic RGD Myocardial autophagy variation during acute myocardial infarction in rats: the effects of carvedilol. 20079142

2009

Entrez Id: 6423
Gene Symbol: SFRP2
SFRP2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.210 Biomarker RGD Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a. 19109969

2009