×
Entrez Id:
498
Gene Symbol:
ATP5F1A
ATP5F1A
Alzheimer's Disease
0.540
Therapeutic
RGD
Protein Drug Targets of Lavandula angustifolia on treatment of Rat Alzheimer's Disease.
25561935
2015
×
Entrez Id:
3480
Gene Symbol:
IGF1R
IGF1R
Alzheimer's Disease
0.560
Therapeutic
RGD
Xanthoceraside attenuates learning and memory deficits via improving insulin signaling in STZ-induced AD rats.
23562514
2013
×
Entrez Id:
3480
Gene Symbol:
IGF1R
IGF1R
Alzheimer's Disease
0.560
Biomarker
RGD
While these disturbances were mostly corrected by restoring receptor function, blockade of the IGF-I receptor exacerbated AD -like pathology in old mutant mice already affected of brain amyloidosis and cognitive derangement.
16274856
2006
×
Entrez Id:
3481
Gene Symbol:
IGF2
IGF2
Alzheimer's Disease
0.570
Biomarker
RGD
Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease.
16627931
2006
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699
2018
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274
2018
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699
2018
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274
2018
×
Entrez Id:
3416
Gene Symbol:
IDE
IDE
Alzheimer's Disease
0.600
Therapeutic
RGD
Treadmill Exercise Ameliorates Spatial Learning and Memory Deficits Through Improving the Clearance of Peripheral and Central Amyloid-Beta Levels.
29948724
2018
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
Effects of Lignans from Schisandra chinensis Rattan Stems against Aβ
29642617
2018
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
Neuroprotective Effect of Nanodiamond in Alzheimer's Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling.
26897372
2017
×
Entrez Id:
3416
Gene Symbol:
IDE
IDE
Alzheimer's Disease
0.600
Therapeutic
RGD
Multifunctional Compound AD-35 Improves Cognitive Impairment and Attenuates the Production of TNF-α and IL-1β in an Aβ25-35-induced Rat Model of Alzheimer's Disease.
28157092
2017
×
Entrez Id:
3416
Gene Symbol:
IDE
IDE
Alzheimer's Disease
0.600
Therapeutic
RGD
Neuroprotective mechanism of
28553348
2017
×
Entrez Id:
3416
Gene Symbol:
IDE
IDE
Alzheimer's Disease
0.600
Therapeutic
RGD
Pioglitazone ameliorates Aβ42 deposition in rats with diet-induced insulin resistance associated with AKT/GSK3β activation.
28447730
2017
×
Entrez Id:
23621
Gene Symbol:
BACE1
BACE1
Alzheimer's Disease
0.600
Therapeutic
RGD
We found that NP03 rescued key initiating components of AD pathology, including inactivating GSK-3β, reducing BACE1 expression and activity, and reducing amyloid levels.
28763060
2017
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Alzheimer's Disease
0.600
Therapeutic
RGD
Amyloid beta lowering and cognition enhancing effects of ghrelin receptor analog [D-Lys (3)] GHRP-6 in rat model of obesity.
25296496
2014
×
Entrez Id:
627
Gene Symbol:
BDNF
BDNF
Alzheimer's Disease
0.600
Therapeutic
RGD
Decreased cell proliferation with decrement of BDNF and TrkB expressions in the hippocampus were observed in the STZ-induced Alzheimer's disease rats.
24877042
2014
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Alzheimer's Disease
0.600
Therapeutic
RGD
Potential therapeutic effect of nanobased formulation of rivastigmine on rat model of Alzheimer's disease.
23378761
2013
×
Entrez Id:
4852
Gene Symbol:
NPY
NPY
Alzheimer's Disease
0.600
Therapeutic
RGD
We suggest that NPY , perhaps acting via NPY Y1 receptors, might interact with the endogenous cholinergic system and play a role in improving the learning and memory processes in the rats with AD -like condition.
22266216
2012
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Alzheimer's Disease
0.600
Biomarker
RGD
Akebia Saponin D attenuates amyloid β-induced cognitive deficits and inflammatory response in rats: involvement of Akt/NF-κB pathway.
22963993
2012
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
"Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD , and the therapeutic effect depends on the integrity of the olfactory nerve pathway.
21585051
2011
×
Entrez Id:
627
Gene Symbol:
BDNF
BDNF
Alzheimer's Disease
0.600
Biomarker
RGD
[Effects of proBDNF on cell proliferation and differentiation in hippocampal dentate gyrus in Alzheimer' disease rat model].
20646587
2010
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Biomarker
RGD
[Effects of TX0201 abstracted from heart-regulating formula on spatial learning and regulation of Bax mRNA, Bcl-2 mRNA level in brain of rat with Alzheimer's disease ].
17639989
2007
×
Entrez Id:
3643
Gene Symbol:
INSR
INSR
Alzheimer's Disease
0.600
Biomarker
RGD
Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease.
16627931
2006
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Biomarker
RGD
Induction of Bcl-2 and Bax was related to hyperphosphorylation of tau and neuronal death induced by okadaic acid in rat brain.
16265626
2005